Dermoscopic Follow-Up of the Skin towards Acute Graft-versus-Host-Disease in Patients after Allogeneic Hematopoietic Stem Cell Transplantation
Joint Authors
Kaminska-Winciorek, Grazyna
Czerw, Tomasz
Kruzel, Tomasz
Giebel, Sebastian
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-30
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
Acute graft-versus-host disease (aGVHD) involving skin is one of the most frequent complications of allogeneic hematopoietic stem cell transplantation (alloHSCT), usually diagnosed based on clinical manifestations.
So far, skin biopsy with histopathological evaluation is the only method to confirm the diagnosis.
Objective.
In this prospective study we monitored alloHSCT recipients by dermoscopy in order to assess its utility as an alternative noninvasive tool to early diagnose acute GVHD.
Methods.
Thirteen consecutive patients who received alloHSCT were examined clinically and dermoscopically towards aGVHD [days 28 (±7), 56 (±7), and 100 (±7)], as well as in each patient who developed cutaneous aGVHD diagnosed according to clinical criteria (Glucksberg scale).
Results.
Six patients (46%) developed symptoms of cutaneous acute GVHD (grade 1, n = 3 ; grade 2, n = 3 ).
Dermoscopic evaluation revealed pinkish or reddish background and well-visible, multiple thin telangiectasias.
Conclusion.
To our knowledge, this is the first report on the use of dermoscopy to evaluate skin involvement in the course of acute GVHD suggesting its role as a diagnostic tool in follow-up of GVHD, which can be also used before clinical symptoms occur.
American Psychological Association (APA)
Kaminska-Winciorek, Grazyna& Czerw, Tomasz& Kruzel, Tomasz& Giebel, Sebastian. 2016. Dermoscopic Follow-Up of the Skin towards Acute Graft-versus-Host-Disease in Patients after Allogeneic Hematopoietic Stem Cell Transplantation. BioMed Research International،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1097807
Modern Language Association (MLA)
Kaminska-Winciorek, Grazyna…[et al.]. Dermoscopic Follow-Up of the Skin towards Acute Graft-versus-Host-Disease in Patients after Allogeneic Hematopoietic Stem Cell Transplantation. BioMed Research International No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1097807
American Medical Association (AMA)
Kaminska-Winciorek, Grazyna& Czerw, Tomasz& Kruzel, Tomasz& Giebel, Sebastian. Dermoscopic Follow-Up of the Skin towards Acute Graft-versus-Host-Disease in Patients after Allogeneic Hematopoietic Stem Cell Transplantation. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1097807
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1097807