Therapeutic Drug Monitoring of Meropenem in Neonate with Necrotizing Enterocolitis: A Challenge
Joint Authors
De Keukeleire, Steven
Borrey, Daniëlle
Decaluwe, Wim
Reynders, Marijke
Source
Case Reports in Infectious Diseases
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-09-15
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Necrotizing enterocolitis (NEC) continues to be a major cause of neonatal morbidity and mortality.
We describe the added value of therapeutic drug monitoring by presenting the case of a preterm infant with severe NEC treated with meropenem.
Dosing strategy will achieve adequate patient outcome when treating pathogens with elevated MIC.
As safe as meropenem is, there are not enough data for 40 mg/kg, every 8 h infused over 4 h; accordingly, strict monitoring of blood levels is mandatory.
Based on our findings, a 4 h prolonged infusion of 40 mg/kg meropenem, every 8 h, will achieve an adequate patient outcome.
American Psychological Association (APA)
De Keukeleire, Steven& Borrey, Daniëlle& Decaluwe, Wim& Reynders, Marijke. 2016. Therapeutic Drug Monitoring of Meropenem in Neonate with Necrotizing Enterocolitis: A Challenge. Case Reports in Infectious Diseases،Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1101004
Modern Language Association (MLA)
De Keukeleire, Steven…[et al.]. Therapeutic Drug Monitoring of Meropenem in Neonate with Necrotizing Enterocolitis: A Challenge. Case Reports in Infectious Diseases No. 2016 (2016), pp.1-3.
https://search.emarefa.net/detail/BIM-1101004
American Medical Association (AMA)
De Keukeleire, Steven& Borrey, Daniëlle& Decaluwe, Wim& Reynders, Marijke. Therapeutic Drug Monitoring of Meropenem in Neonate with Necrotizing Enterocolitis: A Challenge. Case Reports in Infectious Diseases. 2016. Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1101004
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1101004