Genetic variation of trichomonas vaginalis isolates from Iraqi women : association with fertility and cervical abnormalities
Other Title(s)
التغاير الوراثي لعزلات طفيلي المشعرات المهبلية المعزول من النساء العراقيات : علاقته مع الخصوبة و تشوهات عنق الرحم
Joint Authors
al-Riyahi, Fula Abd al-Sattar
Mirdaw, Maysun Abd al-Zahrah
al-Bashir, Nada Muhammad Taha
al-Tai, Lazim Hamid Kayid
Kazim, Haydar Sabah
Source
Journal of Babylon University : Journal of Applied and Pure Sciences
Issue
Vol. 26, Issue 7 (31 Jul. 2018), pp.321-338, 18 p.
Publisher
Publication Date
2018-07-31
Country of Publication
Iraq
No. of Pages
18
Main Subjects
Topics
Abstract EN
Background: Trichomoniasis, is one of the most common non-viral sexually transmitted diseases caused by the parasite Trichomonas vaginalis.
Little is known about the genetic diversity and population structure of this parasite.
This study aimed to determine the genetic diversity of T.
vaginalis isolated from Iraqi women and its association with the fertility and the cervical abnormalities.
Methods: Overall, 154 Iraqi women attending the Gynecology Outpatient departments in Baghdad Province, Iraq from February 2013 to April 2014, were enrolled in this study.
DNA of T.
vaginalis isolates was extracted from the culture ofhigh vaginal swabs.
Multilocus sequence typing (MLST) method for six housekeeping genes was done in studying the genetic variations.
Results: Fifty-three women (34.41%) were positive for T.
vaginalis.
MLST method resulted in different alleles.
With glutaminase gene, the highest degree of variation was found among the six genes.
Conclusion: The genetic diversity in the organism itself in Iraqi isolates can associate with clinical outcome.
Further MLST studies are needed to compare a larger number of isolates from different localities and correlate the certain mutations in housekeeping genes to infertile women and patients with cervical abnormalities.
American Psychological Association (APA)
Mirdaw, Maysun Abd al-Zahrah& Kazim, Haydar Sabah& al-Riyahi, Fula Abd al-Sattar& al-Bashir, Nada Muhammad Taha& al-Tai, Lazim Hamid Kayid. 2018. Genetic variation of trichomonas vaginalis isolates from Iraqi women : association with fertility and cervical abnormalities. Journal of Babylon University : Journal of Applied and Pure Sciences،Vol. 26, no. 7, pp.321-338.
https://search.emarefa.net/detail/BIM-1101043
Modern Language Association (MLA)
Mirdaw, Maysun Abd al-Zahrah…[et al.]. Genetic variation of trichomonas vaginalis isolates from Iraqi women : association with fertility and cervical abnormalities. Journal of Babylon University : Journal of Applied and Pure Sciences Vol. 26, no. 7 (2018), pp.321-338.
https://search.emarefa.net/detail/BIM-1101043
American Medical Association (AMA)
Mirdaw, Maysun Abd al-Zahrah& Kazim, Haydar Sabah& al-Riyahi, Fula Abd al-Sattar& al-Bashir, Nada Muhammad Taha& al-Tai, Lazim Hamid Kayid. Genetic variation of trichomonas vaginalis isolates from Iraqi women : association with fertility and cervical abnormalities. Journal of Babylon University : Journal of Applied and Pure Sciences. 2018. Vol. 26, no. 7, pp.321-338.
https://search.emarefa.net/detail/BIM-1101043
Data Type
Journal Articles
Language
English
Notes
Record ID
BIM-1101043