Myeloproliferative Disease: An Unusual Cause of Raynaud’s Phenomenon and Digital Ischaemia
Joint Authors
Beynon, Celia
Huws, Gwenan
Lawson, Tom
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-2, 2 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-11-08
Country of Publication
Egypt
No. of Pages
2
Main Subjects
Abstract EN
We describe a 59-year-old female who presented with ischaemic digits, preceded by a 6-month history of Raynaud’s phenomenon affecting her fingers and toes.
There were no clinical or laboratory features of primary vasculitis or connective tissue disease, Doppler imaging was normal, and bloods were unremarkable aside from a platelet count of 786 × 109/L (150–400) and white cells of 16 × 109/L (4–11).
In view of the thrombocytosis a JAK2 mutation assay was requested which confirmed a JAK2 V617F mutation, suggesting essential thrombocytosis (ET) as the cause.
She received treatment with hydroxycarbamide which normalised her platelet count and led to a complete resolution of her Raynaud’s symptoms.
Raynaud’s phenomenon is a rare manifestation of ET.
Myeloproliferative disorders such as ET should be considered in the differential diagnosis of Raynaud’s phenomenon and vasculitis.
American Psychological Association (APA)
Beynon, Celia& Huws, Gwenan& Lawson, Tom. 2016. Myeloproliferative Disease: An Unusual Cause of Raynaud’s Phenomenon and Digital Ischaemia. Case Reports in Medicine،Vol. 2016, no. 2016, pp.1-2.
https://search.emarefa.net/detail/BIM-1101199
Modern Language Association (MLA)
Beynon, Celia…[et al.]. Myeloproliferative Disease: An Unusual Cause of Raynaud’s Phenomenon and Digital Ischaemia. Case Reports in Medicine No. 2016 (2016), pp.1-2.
https://search.emarefa.net/detail/BIM-1101199
American Medical Association (AMA)
Beynon, Celia& Huws, Gwenan& Lawson, Tom. Myeloproliferative Disease: An Unusual Cause of Raynaud’s Phenomenon and Digital Ischaemia. Case Reports in Medicine. 2016. Vol. 2016, no. 2016, pp.1-2.
https://search.emarefa.net/detail/BIM-1101199
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1101199