A Child with Local Lipohypertrophy following Recombinant Human Growth Hormone Administration

Joint Authors

Koppen, Ilan J. N.
Bakx, Roel
de Kruiff, Chris C.
van Trotsenburg, A. S. Paul

Source

Case Reports in Pediatrics

Issue

Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-4, 4 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2016-10-10

Country of Publication

Egypt

No. of Pages

4

Main Subjects

Medicine

Abstract EN

Local lipohypertrophy due to recombinant human growth hormone (rhGH) administration is a rare phenomenon.

Here, we report a case of an 11-year-old girl who presented with a paraumbilical swelling, approximately one year after the start of rhGH treatment for short stature due to the presumed diagnosis of partial growth hormone insensitivity.

Ultrasound imaging revealed an asymmetric distribution of subcutaneous fat tissue at the rhGH administration site, indicating local lipohypertrophy.

After sparing her routine injection site and alternating other sites, the swelling disappeared within 6 months.

Although the precise cause of local lipohypertrophy resulting from rhGH administration is still unclear, it might be related to the presumed diagnosis of partial growth hormone insensitivity.

American Psychological Association (APA)

Koppen, Ilan J. N.& Bakx, Roel& de Kruiff, Chris C.& van Trotsenburg, A. S. Paul. 2016. A Child with Local Lipohypertrophy following Recombinant Human Growth Hormone Administration. Case Reports in Pediatrics،Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1102466

Modern Language Association (MLA)

Koppen, Ilan J. N.…[et al.]. A Child with Local Lipohypertrophy following Recombinant Human Growth Hormone Administration. Case Reports in Pediatrics No. 2016 (2016), pp.1-4.
https://search.emarefa.net/detail/BIM-1102466

American Medical Association (AMA)

Koppen, Ilan J. N.& Bakx, Roel& de Kruiff, Chris C.& van Trotsenburg, A. S. Paul. A Child with Local Lipohypertrophy following Recombinant Human Growth Hormone Administration. Case Reports in Pediatrics. 2016. Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1102466

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1102466