The Role of MR Enterography in Assessing Crohn’s Disease Activity and Treatment Response
Joint Authors
Moy, Matthew P.
Sauk, Jenny
Gee, Michael S.
Source
Gastroenterology Research and Practice
Issue
Vol. 2016, Issue 2016 (31 Dec. 2015), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-12-27
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
MR enterography (MRE) has become the primary imaging modality in the assessment of Crohn’s disease (CD) in both children and adults at many institutions in the United States and worldwide, primarily due to its noninvasiveness, superior soft tissue contrast, and lack of ionizing radiation.
MRE technique includes distention of the small bowel with oral contrast media with the acquisition of T2-weighted, balanced steady-state free precession, and multiphase T1-weighted fat suppressed gadolinium contrast-enhanced sequences.
With the introduction of molecule-targeted biologic agents into the clinical setting for CD and their potential to reverse the inflammatory process, MRE is increasingly utilized to evaluate disease activity and response to therapy as an imaging complement to clinical indices or optical endoscopy.
New and emerging MRE techniques, such as diffusion-weighted imaging (DWI), magnetization transfer, ultrasmall superparamagnetic iron oxide- (USPIO-) enhanced MRI, and PET-MR, offer the potential for an expanded role of MRI in detecting occult disease activity, evaluating early treatment response/resistance, and differentiating inflammatory from fibrotic strictures.
Familiarity with MR enterography is essential for radiologists and gastroenterologists as the technique evolves and is further incorporated into the clinical management of CD.
American Psychological Association (APA)
Moy, Matthew P.& Sauk, Jenny& Gee, Michael S.. 2015. The Role of MR Enterography in Assessing Crohn’s Disease Activity and Treatment Response. Gastroenterology Research and Practice،Vol. 2016, no. 2016, pp.1-13.
https://search.emarefa.net/detail/BIM-1104801
Modern Language Association (MLA)
Moy, Matthew P.…[et al.]. The Role of MR Enterography in Assessing Crohn’s Disease Activity and Treatment Response. Gastroenterology Research and Practice Vol. 2016, no. 2016 (2015), pp.1-13.
https://search.emarefa.net/detail/BIM-1104801
American Medical Association (AMA)
Moy, Matthew P.& Sauk, Jenny& Gee, Michael S.. The Role of MR Enterography in Assessing Crohn’s Disease Activity and Treatment Response. Gastroenterology Research and Practice. 2015. Vol. 2016, no. 2016, pp.1-13.
https://search.emarefa.net/detail/BIM-1104801
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104801