Localisation of Lactate Transporters in Rat and Rabbit Placentae
Joint Authors
Moore, Nigel P.
Picut, Catherine A.
Charlap, Jeffrey H.
Source
International Journal of Cell Biology
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-23
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The distribution of monocarboxylate transporter (MCT) isoforms 1 and 4, which mediate the plasmalemmal transport of l-lactic and pyruvic acids, has been identified in the placentae of rats and rabbits at different ages of gestation.
Groups of three pregnant Sprague-Dawley rats and New Zealand White rabbits were sacrificed on gestation days (GD) 11, 14, 18, or 20 and on GD 13, 18, or 28, respectively.
Placentae were removed and processed for immunohistochemical detection of MCT1 and MCT4.
In the rat, staining for MCT1 was associated with lakes and blood vessels containing enucleated red blood cells (maternal vessels) while staining for MCT4 was associated with vessels containing nucleated red blood cells (embryofoetal vessels).
In the rabbit, staining for MCT1 was associated with blood vessels containing nucleated red blood cells while staining for MCT4 was associated with vessels containing enucleated red blood cells.
Strength of staining for MCT1 decreased during gestation in both species, but that for MCT4 was stronger than that for MCT1 and was consistent between gestation days.
The results imply an opposite polarity of MCT1 and MCT4 across the trophoblast between rat and rabbit.
American Psychological Association (APA)
Moore, Nigel P.& Picut, Catherine A.& Charlap, Jeffrey H.. 2016. Localisation of Lactate Transporters in Rat and Rabbit Placentae. International Journal of Cell Biology،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1105503
Modern Language Association (MLA)
Moore, Nigel P.…[et al.]. Localisation of Lactate Transporters in Rat and Rabbit Placentae. International Journal of Cell Biology No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1105503
American Medical Association (AMA)
Moore, Nigel P.& Picut, Catherine A.& Charlap, Jeffrey H.. Localisation of Lactate Transporters in Rat and Rabbit Placentae. International Journal of Cell Biology. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1105503
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1105503