Synthesis, Properties, and In Vitro Hydrolytic Degradation of Poly(d,l-lactide-co-glycolide-co-ε-caprolactone)
Joint Authors
Liu, Yixiu
Bai, Xizhuang
Liang, A.
Source
International Journal of Polymer Science
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-20
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Random copolymers of poly(d,l-lactide-co-glycolide-co-ε-caprolactone) (PLGC) were synthesized by the ring-opening polymerization of d,l-lactide (DLLA), glycolide (GA), and ε-caprolactone (CL).
The effects of CL on the copolymers were evaluated to prepare suitable copolymers with controlled properties.
Our results showed that the CL content significantly influenced the thermal and mechanical properties of the copolymers and that the CL content in compositions could be altered to control properties of random copolymers.
The in vitro hydrolytic degradation of the resulting implants showed that the degradation rate of PLGC was lower than that of PLGA, which could markedly reduce acidic degradation products.
Finally, we demonstrated that higher CL contents in compositions slowed degradation rates.
American Psychological Association (APA)
Liu, Yixiu& Bai, Xizhuang& Liang, A.. 2016. Synthesis, Properties, and In Vitro Hydrolytic Degradation of Poly(d,l-lactide-co-glycolide-co-ε-caprolactone). International Journal of Polymer Science،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1106860
Modern Language Association (MLA)
Liu, Yixiu…[et al.]. Synthesis, Properties, and In Vitro Hydrolytic Degradation of Poly(d,l-lactide-co-glycolide-co-ε-caprolactone). International Journal of Polymer Science No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1106860
American Medical Association (AMA)
Liu, Yixiu& Bai, Xizhuang& Liang, A.. Synthesis, Properties, and In Vitro Hydrolytic Degradation of Poly(d,l-lactide-co-glycolide-co-ε-caprolactone). International Journal of Polymer Science. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1106860
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1106860