Synthesis, Properties, and In Vitro Hydrolytic Degradation of Poly(d,l-lactide-co-glycolide-co-ε-caprolactone)‎

Joint Authors

Liu, Yixiu
Bai, Xizhuang
Liang, A.

Source

International Journal of Polymer Science

Issue

Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2016-06-20

Country of Publication

Egypt

No. of Pages

9

Main Subjects

Physics

Abstract EN

Random copolymers of poly(d,l-lactide-co-glycolide-co-ε-caprolactone) (PLGC) were synthesized by the ring-opening polymerization of d,l-lactide (DLLA), glycolide (GA), and ε-caprolactone (CL).

The effects of CL on the copolymers were evaluated to prepare suitable copolymers with controlled properties.

Our results showed that the CL content significantly influenced the thermal and mechanical properties of the copolymers and that the CL content in compositions could be altered to control properties of random copolymers.

The in vitro hydrolytic degradation of the resulting implants showed that the degradation rate of PLGC was lower than that of PLGA, which could markedly reduce acidic degradation products.

Finally, we demonstrated that higher CL contents in compositions slowed degradation rates.

American Psychological Association (APA)

Liu, Yixiu& Bai, Xizhuang& Liang, A.. 2016. Synthesis, Properties, and In Vitro Hydrolytic Degradation of Poly(d,l-lactide-co-glycolide-co-ε-caprolactone). International Journal of Polymer Science،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1106860

Modern Language Association (MLA)

Liu, Yixiu…[et al.]. Synthesis, Properties, and In Vitro Hydrolytic Degradation of Poly(d,l-lactide-co-glycolide-co-ε-caprolactone). International Journal of Polymer Science No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1106860

American Medical Association (AMA)

Liu, Yixiu& Bai, Xizhuang& Liang, A.. Synthesis, Properties, and In Vitro Hydrolytic Degradation of Poly(d,l-lactide-co-glycolide-co-ε-caprolactone). International Journal of Polymer Science. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1106860

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1106860