A Multicenter Retrospective Survey regarding Diabetic Ketoacidosis Management in Italian Children with Type 1 Diabetes
Joint Authors
Zucchini, Stefano
Bonfanti, Riccardo
Buono, Pietro
Cardella, Francesca
Cauvin, Vittoria
Cherubini, Valentino
Chiari, Giovanni
d’Annunzio, Giuseppe
Frongia, Anna Paola
Iafusco, Dario
Maltoni, Giulio
Patera, Ippolita Patrizia
Toni, Sonia
Tumini, Stefano
Rabbone, Ivana
Diabetes Study Group of the Italian Society for Pediatric Endocrinology and Diabetology (ISPED), Ivana
Scaramuzza, Andrea
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-11-15
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
We conducted a retrospective survey in pediatric centers belonging to the Italian Society for Pediatric Diabetology and Endocrinology.
The following data were collected for all new-onset diabetes patients aged 0–18 years: DKA (pH < 7.30), severe DKA (pH < 7.1), DKA in preschool children, DKA treatment according to ISPAD protocol, type of rehydrating solution used, bicarbonates use, and amount of insulin infused.
Records ( n = 2453 ) of children with newly diagnosed diabetes were collected from 68/77 centers (87%), 39 of which are tertiary referral centers, the majority of whom ( n = 1536 , 89.4%) were diagnosed in the tertiary referral centers.
DKA was observed in 38.5% and severe DKA in 10.3%.
Considering preschool children, DKA was observed in 72%, and severe DKA in 16.7%.
Cerebral edema following DKA treatment was observed in 5 (0.5%).
DKA treatment according to ISPAD guidelines was adopted in 68% of the centers.
In the first 2 hours, rehydration was started with normal saline in all centers, but with different amount.
Bicarbonate was quite never been used.
Insulin was infused starting from third hour at the rate of 0.05–0.1 U/kg/h in 72% of centers.
Despite prevention campaign, DKA is still observed in Italian children at onset, with significant variability in DKA treatment, underlying the need to share guidelines among centers.
American Psychological Association (APA)
Zucchini, Stefano& Scaramuzza, Andrea& Bonfanti, Riccardo& Buono, Pietro& Cardella, Francesca& Cauvin, Vittoria…[et al.]. 2015. A Multicenter Retrospective Survey regarding Diabetic Ketoacidosis Management in Italian Children with Type 1 Diabetes. Journal of Diabetes Research،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1108167
Modern Language Association (MLA)
Zucchini, Stefano…[et al.]. A Multicenter Retrospective Survey regarding Diabetic Ketoacidosis Management in Italian Children with Type 1 Diabetes. Journal of Diabetes Research No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1108167
American Medical Association (AMA)
Zucchini, Stefano& Scaramuzza, Andrea& Bonfanti, Riccardo& Buono, Pietro& Cardella, Francesca& Cauvin, Vittoria…[et al.]. A Multicenter Retrospective Survey regarding Diabetic Ketoacidosis Management in Italian Children with Type 1 Diabetes. Journal of Diabetes Research. 2015. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1108167
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1108167