Structural and Biological Assessment of Zinc Doped Hydroxyapatite Nanoparticles
Joint Authors
Popa, Cristina Liana
Deniaud, Aurélien
Michaud-Soret, Isabelle
Guégan, Régis
Predoi, Daniela
Motelica-Heino, Mikael
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-30
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The aim of the current research work was to study the physicochemical and biological properties of synthesized zinc doped hydroxyapatite (ZnHAp) nanoparticles with Zn concentrations x Zn = 0 (HAp), x Zn = 0.07 (7ZnHAp), and x Zn = 0.1 (10ZnHAp) for potential use in biological applications.
The morphology, size, compositions, and incorporation of zinc into hydroxyapatite were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), Fourier Transform Infrared Spectroscopy (FTIR), Raman scattering, and X-Ray Photoelectron Spectroscopy (XPS).
In addition, the cytotoxicity of ZnHAp nanoparticles was tested on both E.
coli bacteria and human hepatocarcinoma cell line HepG2.
The results showed that ZnHAp nanoparticles (HAp, 7ZnHAp, and 10ZnHAp) have slightly elongated morphologies with average diameters between 25 nm and 18 nm.
On the other hand, a uniform and homogeneous distribution of the constituent elements (calcium, phosphorus, zinc, and oxygen) in the ZnHAp powder was noticed.
Besides, FTIR and Raman analyses confirmed the proper hydroxyapatite structure of the synthesized ZnHAp nanoparticles with the signature of phosphate, carbonate, and hydroxyl groups.
Moreover, it can be concluded that Zn doping at the tested concentrations is not inducing a specific prokaryote or eukaryote toxicity in HAp compounds.
American Psychological Association (APA)
Popa, Cristina Liana& Deniaud, Aurélien& Michaud-Soret, Isabelle& Guégan, Régis& Motelica-Heino, Mikael& Predoi, Daniela. 2016. Structural and Biological Assessment of Zinc Doped Hydroxyapatite Nanoparticles. Journal of Nanomaterials،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1108992
Modern Language Association (MLA)
Popa, Cristina Liana…[et al.]. Structural and Biological Assessment of Zinc Doped Hydroxyapatite Nanoparticles. Journal of Nanomaterials No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1108992
American Medical Association (AMA)
Popa, Cristina Liana& Deniaud, Aurélien& Michaud-Soret, Isabelle& Guégan, Régis& Motelica-Heino, Mikael& Predoi, Daniela. Structural and Biological Assessment of Zinc Doped Hydroxyapatite Nanoparticles. Journal of Nanomaterials. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1108992
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1108992