Euterpe edulis Extract but Not Oil Enhances Antioxidant Defenses and Protects against Nonalcoholic Fatty Liver Disease Induced by a High-Fat Diet in Rats
Joint Authors
Leite, João Paulo Viana
Lima, Luciana Moreira
Novaes, Rômulo Dias
Gonçalves, Reggiani Vilela
Freitas, Rodrigo Barros
Mendonça, Bianca Gazolla
Santos, Eliziária Cardoso
Fietto, Luciano Gomes
Peluzio, Maria do Carmo Gouveia
Ribeiro, Andréia Queiroz
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-23
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
We investigated the effects of E.
edulis bioproducts (lyophilized pulp [LEE], defatted lyophilized pulp [LDEE], and oil [EO]) on nonalcoholic fatty liver disease (NAFLD) induced by a high-fat diet (HFD) in rats.
All products were chemically analyzed.
In vivo, 42 rats were equally randomized into seven groups receiving standard diet, HFD alone or combined with EO, LEE, or LDEE.
After NAFLD induction, LEE, LDEE, or EO was added to the animals’ diet for 4 weeks.
LEE was rich in polyunsaturated fatty acids.
From LEE degreasing, LDEE presented higher levels of anthocyanins and antioxidant capacity in vitro.
Dietary intake of LEE and especially LDEE, but not EO, attenuated diet-induced NAFLD, reducing inflammatory infiltrate, steatosis, and lipid peroxidation in liver tissue.
Although both E.
edulis bioproducts were not hepatotoxic, only LDEE presented sufficient benefits to treat NAFLD in rats, possibly by its low lipid content and high amount of phenols and anthocyanins.
American Psychological Association (APA)
Freitas, Rodrigo Barros& Novaes, Rômulo Dias& Gonçalves, Reggiani Vilela& Mendonça, Bianca Gazolla& Santos, Eliziária Cardoso& Ribeiro, Andréia Queiroz…[et al.]. 2016. Euterpe edulis Extract but Not Oil Enhances Antioxidant Defenses and Protects against Nonalcoholic Fatty Liver Disease Induced by a High-Fat Diet in Rats. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1114294
Modern Language Association (MLA)
Freitas, Rodrigo Barros…[et al.]. Euterpe edulis Extract but Not Oil Enhances Antioxidant Defenses and Protects against Nonalcoholic Fatty Liver Disease Induced by a High-Fat Diet in Rats. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1114294
American Medical Association (AMA)
Freitas, Rodrigo Barros& Novaes, Rômulo Dias& Gonçalves, Reggiani Vilela& Mendonça, Bianca Gazolla& Santos, Eliziária Cardoso& Ribeiro, Andréia Queiroz…[et al.]. Euterpe edulis Extract but Not Oil Enhances Antioxidant Defenses and Protects against Nonalcoholic Fatty Liver Disease Induced by a High-Fat Diet in Rats. Oxidative Medicine and Cellular Longevity. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1114294
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1114294