Median and Ulnar Neuropathy Assessment in Parkinson’s Disease regarding Symptom Severity and Asymmetry
Joint Authors
Yardimci, Nilgul
Cemeroglu, Ozlem
Ozturk, Eda
Gürlü, Gülsüm
Şahin, Esra
Bozkurt, Saliha
Cengiz, Tugba
Karali, Gulderen
Cakirbay, Hasim
İlhan, Atilla
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-24
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
While increasing evidence suggests comorbidity of peripheral neuropathy (PNP) and Parkinson’s disease (PD), the pathogenesis of PNP in PD is still a debate.
The aim of this article is to search the core PD symptoms such as rigidity and tremor as contributing factors to mononeuropathy development while emphasizing each individual patient’s asymmetric symptom severity.
Methods.
We studied 62 wrists and 62 elbows of 31 patients (mean age 66.48±10.67) and 64 wrists and 64 elbows of 32 age-gender matched healthy controls (mean age 62.03±10.40, p=0.145).
The Hoehn and Yahr disability scale and Unified Parkinson’s Disease Rated Scale were used to determine the severity of the disease.
Results.
According to electrodiagnostic criteria, we confirmed median neuropathy in 16.12% (bilateral in two-thirds of the patients) and ulnar neuropathy in 3.22% of the PD group.
While mean age (p=0.003), age at PD onset (p=0.019), and H&Y scores (p=0.016) were significant, tremor and rigidity scores were not.
The comparison of the mean indices of electrophysiologic parameters indicated subclinical median and ulnar nerve demyelination both at the wrist and at the elbow in the patient groups where a longer disease duration and mild tremor and rigidity scores are prominent, remarkably.
Conclusion.
A disease related peripheral neurodegeneration beyond symptom severity occurs in PD.
American Psychological Association (APA)
Yardimci, Nilgul& Cemeroglu, Ozlem& Ozturk, Eda& Gürlü, Gülsüm& Şahin, Esra& Bozkurt, Saliha…[et al.]. 2016. Median and Ulnar Neuropathy Assessment in Parkinson’s Disease regarding Symptom Severity and Asymmetry. Parkinson’s Disease،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1115239
Modern Language Association (MLA)
Yardimci, Nilgul…[et al.]. Median and Ulnar Neuropathy Assessment in Parkinson’s Disease regarding Symptom Severity and Asymmetry. Parkinson’s Disease No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1115239
American Medical Association (AMA)
Yardimci, Nilgul& Cemeroglu, Ozlem& Ozturk, Eda& Gürlü, Gülsüm& Şahin, Esra& Bozkurt, Saliha…[et al.]. Median and Ulnar Neuropathy Assessment in Parkinson’s Disease regarding Symptom Severity and Asymmetry. Parkinson’s Disease. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1115239
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1115239