Parkinson’s Disease and Cognitive Impairment
Joint Authors
Tang, Bei-sha
Guo, Jifeng
Yang, Yang
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-12-12
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Parkinson’s disease (PD) is a progressive neurodegenerative disease primarily characterized by the hallmarks of motor symptoms, such as tremor, bradykinesia, rigidity, and postural instability.
However, through clinical investigations in patients and experimental findings in animal models of Parkinson’s disease for years, it is now well recognized that Parkinson’s disease is more than just a motor-deficit disorder.
The majority of Parkinson’s disease patients suffer from nonmotor disabilities, for instance, cognitive impairment, autonomic dysfunction, sensory dysfunction, and sleep disorder.
So far, anti-PD prescriptions and surgical treatments have been mainly focusing on motor dysfunctions, leaving cognitive impairment a marginal clinical field.
Within the nonmotor symptoms, cognitive impairment is one of the most common and significant aspects of Parkinson’s disease, and cognitive deficits such as dysexecutive syndrome and visuospatial disturbances could seriously affect the quality of life, reduce life expectancy, prolong the duration of hospitalization, and therefore increase burdens of caregiver and medical costs.
In this review, we have done a retrospective study of the recent related researches on epidemiology, clinical manifestation and diagnosis, genetics, and potential treatment of cognitive deficits in Parkinson’s disease, aiming to provide a summary of cognitive impairment in Parkinson’s disease and make it easy for clinicians to tackle this challenging issue in their future practice.
American Psychological Association (APA)
Yang, Yang& Tang, Bei-sha& Guo, Jifeng. 2016. Parkinson’s Disease and Cognitive Impairment. Parkinson’s Disease،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1115255
Modern Language Association (MLA)
Yang, Yang…[et al.]. Parkinson’s Disease and Cognitive Impairment. Parkinson’s Disease No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1115255
American Medical Association (AMA)
Yang, Yang& Tang, Bei-sha& Guo, Jifeng. Parkinson’s Disease and Cognitive Impairment. Parkinson’s Disease. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1115255
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1115255