Phytochemical Profiling and Larval Control of Erythrina variegata Methanol Fraction against Malarial and Filarial Vector

Joint Authors

Baranitharan, Mathalaimuthu
Sawicka, Barbara
Gokulakrishnan, Jayapal

Source

Advances in Preventive Medicine

Issue

Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-9, 9 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2019-04-16

Country of Publication

Egypt

No. of Pages

9

Main Subjects

Public Health

Abstract EN

Erythrina variegata (E.

variegata) bioactive chemical has been the potential to be utilized as a good, eco-friendly approach for the control of mosquito population.

In the present investigation, methanol extract using insecticidal compounds isolated against mosquito larvae kill assay was carried out.

Secondary metabolism was characterized by thin layer chromatography, column chromatography, Fourier transform-infrared spectroscopy, gas chromatography-mass spectral, and identification of compound.

Mosquito immature third instar larval, Anopheles stephensi, and Culex quinquefasciatus have been exposed to different concentrations of 50-250 µg/ml.

Totally, larvae were death rate 98.2% (significant value 0.001b) from methanol extract and it is significant toxicity against larvae of An.

stephensi and Cx.

quinquefasciatus with LC50/LC99 values were 157.69/339.55 µg/ml and 137.67/297.33 µg/ml, respectively.

FT-IR analysis in the functional groups such as alcohol, amines, amides, alkenes, 1⁎ amines, aromatic amines, aliphatic amines, 1⁎,2⁎ amines, and alkyl halides searched the identity of secondary metabolites, which may act as 12-Octadecenoic acid, methyl ester compound and clearly indicates being phytochemical.

Chemical constituents of twenty-five compounds were identified in the methanol extract.

The major components were 12-Octadecenoic acid and methyl ester (37.31%).

Compound molecules consist of carbon 19 atoms (gray), hydrogen 36 atoms (greenish blue), and oxygen 2 atoms (red), indicated by the different colors.

The results were obtained suggesting that, in addition to their pharmaceutical and medicine sources, 12-Octadecenoic acid, methyl ester compound can also serve as a natural mosquito control.

American Psychological Association (APA)

Baranitharan, Mathalaimuthu& Sawicka, Barbara& Gokulakrishnan, Jayapal. 2019. Phytochemical Profiling and Larval Control of Erythrina variegata Methanol Fraction against Malarial and Filarial Vector. Advances in Preventive Medicine،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1121777

Modern Language Association (MLA)

Baranitharan, Mathalaimuthu…[et al.]. Phytochemical Profiling and Larval Control of Erythrina variegata Methanol Fraction against Malarial and Filarial Vector. Advances in Preventive Medicine No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1121777

American Medical Association (AMA)

Baranitharan, Mathalaimuthu& Sawicka, Barbara& Gokulakrishnan, Jayapal. Phytochemical Profiling and Larval Control of Erythrina variegata Methanol Fraction against Malarial and Filarial Vector. Advances in Preventive Medicine. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1121777

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1121777