Liver Retraction Using n-Butyl-2-Cyanoacrylate (NBCA) Glue during Laparoscopic Splenectomy and Azygoportal Disconnection in Cirrhotic Patients
Joint Authors
Jiang, Zhengchen
Kong, Du
Wang, Wei
Du, Gang
Shi, Binyao
Jin, Bin
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-08-19
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Although liver retraction using n-butyl-2-cyanoacrylate (NBCA) glue has been applied to laparoscopic upper abdominal surgery in noncirrhotic patients, there is still no consensus on its safety and feasibility for cirrhotic patients.
In this study, we aimed to investigate the safety and effectiveness of liver retraction using NBCA glue during laparoscopic splenectomy and azygoportal disconnection (LSD) for gastroesophageal varices and hypersplenism secondary to liver cirrhosis and portal hypertension.
Methods.
Thirty-nine gastroesophageal varices and hypersplenism secondary to liver cirrhosis and portal hypertension patients were included in our study.
We performed LSD in the presence of NBCA glue (n = 22, NBCA group) and absence of NBCA glue (n = 17, n-NBCA group), respectively.
The operation time, blood loss, postoperative hospitalization, and liver function were compared between the two groups.
Results.
There was no mortality during the operation.
One patient in non-NBCA group received open surgery due to parenchyma hemorrhage.
Postoperative pleural effusion occurred in 2 cases of the NBCA group and 1 of the non-NBCA group.
One showed left subphrenic abscess in the non-NBCA group.
No postoperative bleeding occurred after 9-30 months of follow-up.
The time of operation in NBCA group was significantly shorter than those in n-NBCA group (198.86±17.86 versus 217.81±20.25min, P<0.01).
Blood loss in NBCA group was significantly lower than non-NBCA group (159.09±56.98 versus 212.50±88.51 ml, P<0.05).
The levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were increased on day 1 after LSD and decreased to normal level on day 7 after LSD in both groups.
There was no significant difference in postoperative hospitalization and liver function between the two groups.
Conclusion.
Liver retraction using NBCA glue during LSD for gastroesophageal varices and hypersplenism secondary to liver cirrhosis and portal hypertension is safe, effective, and feasible.
American Psychological Association (APA)
Kong, Du& Wang, Wei& Du, Gang& Shi, Binyao& Jiang, Zhengchen& Jin, Bin. 2018. Liver Retraction Using n-Butyl-2-Cyanoacrylate (NBCA) Glue during Laparoscopic Splenectomy and Azygoportal Disconnection in Cirrhotic Patients. BioMed Research International،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1125603
Modern Language Association (MLA)
Kong, Du…[et al.]. Liver Retraction Using n-Butyl-2-Cyanoacrylate (NBCA) Glue during Laparoscopic Splenectomy and Azygoportal Disconnection in Cirrhotic Patients. BioMed Research International No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1125603
American Medical Association (AMA)
Kong, Du& Wang, Wei& Du, Gang& Shi, Binyao& Jiang, Zhengchen& Jin, Bin. Liver Retraction Using n-Butyl-2-Cyanoacrylate (NBCA) Glue during Laparoscopic Splenectomy and Azygoportal Disconnection in Cirrhotic Patients. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1125603
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1125603