Helicobacter pylori Infection, Virulence Genes’ Distribution and Accompanying Clinical Outcomes: The West Africa Situation
Joint Authors
Ofori, Eric Gyamerah
Adinortey, Cynthia Ayefoumi
Bockarie, Ansumana Sandy
Kyei, Foster
Tagoe, Emmanuel Ayitey
Adinortey, Michael Buenor
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-12-10
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Data on Helicobacter pylori (H.
pylori) infection and virulence factors in countries across West Africa are scattered.
This systematic review seeks to present an update on the status of H.
pylori infection focusing on prevalence rate, distribution of virulent genes, and their link to clinical outcomes across countries in the western part of Africa.
This information is expected to broaden the knowledge base of clinicians and researchers regarding H.
pylori infection and associated virulence factors in West African countries.
Search Method.
A comprehensive search of the scientific literature in PubMed and ScienceDirect was conducted using the search terms including “Helicobacter pylori infection in West Africa”.
Databases were sourced from January 1988 to December 2018.
Results.
Data on the incidence of H.
pylori infection and related pathological factors were found for some countries, whereas others had no information on it.
Smoking, alcohol, exposure to high levels of carcinogens and diet were reported to be involved in the pathogenesis of gastroduodenal diseases and gastric cancer.
Besides the environmental factors and genetic characteristics, there are important characteristics of H.
pylori such as the ability to infect, replicate, and persist in a host that have been associated with the pathogenesis of various gastroduodenal diseases.
Concluding Remarks.
This systematic search has provided information so far available on H.
pylori virulence factors and clinical outcomes in West Africa.
Accordingly, this piece has identified gaps in the body of knowledge highlighting the need for more studies to clarify the role of H.
pylori virulence factors and associated clinical outcomes in the burden of this bacterial infection in West Africa, as data from these countries do not give the needed direct relation.
American Psychological Association (APA)
Ofori, Eric Gyamerah& Adinortey, Cynthia Ayefoumi& Bockarie, Ansumana Sandy& Kyei, Foster& Tagoe, Emmanuel Ayitey& Adinortey, Michael Buenor. 2019. Helicobacter pylori Infection, Virulence Genes’ Distribution and Accompanying Clinical Outcomes: The West Africa Situation. BioMed Research International،Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1127225
Modern Language Association (MLA)
Ofori, Eric Gyamerah…[et al.]. Helicobacter pylori Infection, Virulence Genes’ Distribution and Accompanying Clinical Outcomes: The West Africa Situation. BioMed Research International No. 2019 (2019), pp.1-13.
https://search.emarefa.net/detail/BIM-1127225
American Medical Association (AMA)
Ofori, Eric Gyamerah& Adinortey, Cynthia Ayefoumi& Bockarie, Ansumana Sandy& Kyei, Foster& Tagoe, Emmanuel Ayitey& Adinortey, Michael Buenor. Helicobacter pylori Infection, Virulence Genes’ Distribution and Accompanying Clinical Outcomes: The West Africa Situation. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1127225
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1127225