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Channeling Vision: CaV1.4—A Critical Link in Retinal Signal Transmission
Joint Authors
Waldner, D. M.
Bech-Hansen, N. T.
Stell, W. K.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-09
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Voltage-gated calcium channels (VGCC) are key to many biological functions.
Entry of Ca2+ into cells is essential for initiating or modulating important processes such as secretion, cell motility, and gene transcription.
In the retina and other neural tissues, one of the major roles of Ca2+-entry is to stimulate or regulate exocytosis of synaptic vesicles, without which synaptic transmission is impaired.
This review will address the special properties of one L-type VGCC, CaV1.4, with particular emphasis on its role in transmission of visual signals from rod and cone photoreceptors (hereafter called “photoreceptors,” to the exclusion of intrinsically photoreceptive retinal ganglion cells) to the second-order retinal neurons, and the pathological effects of mutations in the CACNA1F gene which codes for the pore-forming α1F subunit of CaV1.4.
American Psychological Association (APA)
Waldner, D. M.& Bech-Hansen, N. T.& Stell, W. K.. 2018. Channeling Vision: CaV1.4—A Critical Link in Retinal Signal Transmission. BioMed Research International،Vol. 2018, no. 2018, pp.1-14.
https://search.emarefa.net/detail/BIM-1128361
Modern Language Association (MLA)
Waldner, D. M.…[et al.]. Channeling Vision: CaV1.4—A Critical Link in Retinal Signal Transmission. BioMed Research International No. 2018 (2018), pp.1-14.
https://search.emarefa.net/detail/BIM-1128361
American Medical Association (AMA)
Waldner, D. M.& Bech-Hansen, N. T.& Stell, W. K.. Channeling Vision: CaV1.4—A Critical Link in Retinal Signal Transmission. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-14.
https://search.emarefa.net/detail/BIM-1128361
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1128361