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Localization of Glucose Transporter 10 to Hair Cells’ Cuticular Plate in the Mouse Inner Ear
Joint Authors
Lin, Xi
Chen, Bei
Wang, Yunfeng
Geng, Manying
Tang, Wenxue
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-06-14
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
This study aimed to investigate the localization pattern of glucose transporters (Gluts) in mouse cochlea.
Genome-wide gene expression analysis using CodeLink™ bioarrays indicated that Glut1 and Glut10 were highly expressed (~10-fold) in mouse cochlea compared with the other members of glucose transporters (Glut2-6, Glut8, and Glut9).
Semiquantitative RT-PCR and western blotting confirmed that Glut10 expression in mouse cochlea was high throughout the embryogenesis and postnatal development.
Immunofluorescent staining showed that Glut10 protein was localized in the cuticular plate of the outer and inner cochlear hair cells and in the ampullary crest of the vestibular system.
Based on these results, it was supposed that Glut10 may contribute to glucose transport from the endolymph to the hair cells across the cuticular plate.
American Psychological Association (APA)
Chen, Bei& Wang, Yunfeng& Geng, Manying& Lin, Xi& Tang, Wenxue. 2018. Localization of Glucose Transporter 10 to Hair Cells’ Cuticular Plate in the Mouse Inner Ear. BioMed Research International،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1128714
Modern Language Association (MLA)
Chen, Bei…[et al.]. Localization of Glucose Transporter 10 to Hair Cells’ Cuticular Plate in the Mouse Inner Ear. BioMed Research International No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1128714
American Medical Association (AMA)
Chen, Bei& Wang, Yunfeng& Geng, Manying& Lin, Xi& Tang, Wenxue. Localization of Glucose Transporter 10 to Hair Cells’ Cuticular Plate in the Mouse Inner Ear. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1128714
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1128714