Prevalence and Determinants of Low Birth Weight in Ethiopia: A Systematic Review and Meta-Analysis

Abstract EN

Introduction.

Low birth weight (LBW) is the most significant risk factor for neonatal and infant mortality.

It is one of the major public health problems in developing countries.

Although there are various studies on low birth weight, findings were inconsistent and inconclusive.

Therefore, this study was conducted to estimate the national-pooled prevalence of low birth weight and its associated factors in Ethiopia.

Method.

Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline was followed.

This meta-analysis employed a review of both published and unpublished studies conducted in Ethiopia.

The databases used were PubMed, Google Scholar, CINAHL, and African Journals Online.

Relevant search terms for prevalence and determinants of LBW were used to retrieve articles.

The meta-analysis was conducted using STATA 14 software.

Forest plots were used to present the findings.

The Cochran Q test and I2 test statistics were used to test heterogeneity across studies.

Egger’s test was used to assess the publication bias of included studies.

The pooled prevalence and the odds ratios (OR) with 95% confidence intervals (CI) were computed and were presented using forest plots.

Results.

A total of 28 studies, 50,110 newborn babies, were included in this meta-analysis.

The pooled prevalence of LBW in Ethiopia was 14.1% (95% CI = 11.2, 17.1).

Higher variation in the prevalence of LBW in different regions across the country was observed.

Significant association of LBW with sex of the newborn baby, higher odds among female babies (OR = 1.5 (95% CI = 1.2, 1.7)), prematurity (OR = 4.7 (95% CI = 1.5, 14.5)), not attending prenatal care (OR = 1.7 (95% CI = 1.4, 2.2)), pregnancy-induced hypertension (OR = 6.7 (95% CI = 3.5, 12.9)), and newborn babies whose mothers were from rural areas (OR = 1.8 (95% CI = 1.2, 2.6) were the factors associated with low birth weight.

Conclusions.

The prevalence of LBW in Ethiopia was high.

LBW was associated with several maternal and newborn characteristics.

The large disparity of LBW among the different regions in the country needs targeted intervention in areas with higher prevalence.

Particular emphasis should be given to mothers residing in rural areas.

Community-based programs are important to increase the use of prenatal care.