HPTLC Fingerprint Profile and Identification of Antidiabetic and Antioxidant Leads from Bauhinia rufescens L
Joint Authors
Osman, Wadah
Mohammed, Mona S
Khalid, Hassan S
Muddathir, Abdelkhalig
Shantier, Shaza W.
Osman, Bashier
Abdoon, Iman
Source
Advances in Pharmacological and Pharmaceutical Sciences
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-18, 18 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-04-24
Country of Publication
Egypt
No. of Pages
18
Main Subjects
Abstract EN
Diabetes is one of the world’s major health problems, and many reports have supported the role of oxidative stress in the pathogenesis of both type 1 and type 2 diabetes.
The present study aims to evaluate the antidiabetic and antioxidant activity of Bauhinia rufescens, a plant used in Sudanese folkloric medicine for the treatment of diabetes.
It was also aimed to identify isolates and characterize the bioactive antidiabetic and antioxidant compounds using bioactivity-guided fractionation followed by high-performance thin-layer chromatography (HPTLC) autobiography, liquid chromatography-mass spectrometric analysis, and nuclear magnetic resonance (NMR).
Two potential compounds were successfully isolated and identified which may provide new leads for more potent analogues in drug discovery.
American Psychological Association (APA)
Osman, Wadah& Mohammed, Mona S& Khalid, Hassan S& Muddathir, Abdelkhalig& Shantier, Shaza W.& Osman, Bashier…[et al.]. 2020. HPTLC Fingerprint Profile and Identification of Antidiabetic and Antioxidant Leads from Bauhinia rufescens L. Advances in Pharmacological and Pharmaceutical Sciences،Vol. 2020, no. 2020, pp.1-18.
https://search.emarefa.net/detail/BIM-1130080
Modern Language Association (MLA)
Osman, Wadah…[et al.]. HPTLC Fingerprint Profile and Identification of Antidiabetic and Antioxidant Leads from Bauhinia rufescens L. Advances in Pharmacological and Pharmaceutical Sciences No. 2020 (2020), pp.1-18.
https://search.emarefa.net/detail/BIM-1130080
American Medical Association (AMA)
Osman, Wadah& Mohammed, Mona S& Khalid, Hassan S& Muddathir, Abdelkhalig& Shantier, Shaza W.& Osman, Bashier…[et al.]. HPTLC Fingerprint Profile and Identification of Antidiabetic and Antioxidant Leads from Bauhinia rufescens L. Advances in Pharmacological and Pharmaceutical Sciences. 2020. Vol. 2020, no. 2020, pp.1-18.
https://search.emarefa.net/detail/BIM-1130080
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1130080