HPTLC Fingerprint Profile and Identification of Antidiabetic and Antioxidant Leads from Bauhinia rufescens L

Joint Authors

Osman, Wadah
Mohammed, Mona S
Khalid, Hassan S
Muddathir, Abdelkhalig
Shantier, Shaza W.
Osman, Bashier
Abdoon, Iman

Source

Advances in Pharmacological and Pharmaceutical Sciences

Issue

Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-18, 18 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2020-04-24

Country of Publication

Egypt

No. of Pages

18

Main Subjects

Pharmacology

Abstract EN

Diabetes is one of the world’s major health problems, and many reports have supported the role of oxidative stress in the pathogenesis of both type 1 and type 2 diabetes.

The present study aims to evaluate the antidiabetic and antioxidant activity of Bauhinia rufescens, a plant used in Sudanese folkloric medicine for the treatment of diabetes.

It was also aimed to identify isolates and characterize the bioactive antidiabetic and antioxidant compounds using bioactivity-guided fractionation followed by high-performance thin-layer chromatography (HPTLC) autobiography, liquid chromatography-mass spectrometric analysis, and nuclear magnetic resonance (NMR).

Two potential compounds were successfully isolated and identified which may provide new leads for more potent analogues in drug discovery.

American Psychological Association (APA)

Osman, Wadah& Mohammed, Mona S& Khalid, Hassan S& Muddathir, Abdelkhalig& Shantier, Shaza W.& Osman, Bashier…[et al.]. 2020. HPTLC Fingerprint Profile and Identification of Antidiabetic and Antioxidant Leads from Bauhinia rufescens L. Advances in Pharmacological and Pharmaceutical Sciences،Vol. 2020, no. 2020, pp.1-18.
https://search.emarefa.net/detail/BIM-1130080

Modern Language Association (MLA)

Osman, Wadah…[et al.]. HPTLC Fingerprint Profile and Identification of Antidiabetic and Antioxidant Leads from Bauhinia rufescens L. Advances in Pharmacological and Pharmaceutical Sciences No. 2020 (2020), pp.1-18.
https://search.emarefa.net/detail/BIM-1130080

American Medical Association (AMA)

Osman, Wadah& Mohammed, Mona S& Khalid, Hassan S& Muddathir, Abdelkhalig& Shantier, Shaza W.& Osman, Bashier…[et al.]. HPTLC Fingerprint Profile and Identification of Antidiabetic and Antioxidant Leads from Bauhinia rufescens L. Advances in Pharmacological and Pharmaceutical Sciences. 2020. Vol. 2020, no. 2020, pp.1-18.
https://search.emarefa.net/detail/BIM-1130080

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1130080