A Case Report of Accidental Intoxication following Ingestion of Foxglove Confused with Borage: High Digoxinemia without Major Complications
Joint Authors
Colombo, Maria Laura
Negroni, Maria Silvia
Marengo, Arianna
Caruso, Donatella
Tayar, Alessandro
Rubiolo, Patrizia
Giavarini, Flavio
Persampieri, Simone
Davanzo, Franca
Carugo, Stefano
Dell'Agli, Mario
Sangiovanni, Enrico
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-11-29
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Foxglove (Digitalis purpurea L.) leaves are frequently confused with borage (Borago officinalis L.), which is traditionally used as a food ingredient.
Due to the presence of the cardiac glycosides, mostly digitoxin, foxglove leaves are poisonous to human and may be fatal if ingested.
A 55-year-old Caucasian woman complaining weakness, fatigue, nausea, and vomiting was admitted to the Emergency Department.
Her symptoms started following consumption of a home-made savory pie with 5 leaves from a plant bought in a garden nursery as borage.
Digoxinemia was high (10.4 μg/L).
The patient was admitted to the cardiac intensive care unit for electrocardiographic monitoring.
Two days after admission, a single episode of advanced atrioventricular (AV) block was recorded by telemetry, followed by a second-degree AV block episode.
Plasma samples at day 11 were analysed by LC-MS spectrometry, and gitoxin was identified suggesting that this compound may be responsible for the clinical toxicity rather than digoxin.
In the case of Digitalis spp.
poisoning, laboratory data should be interpreted according to the clinical picture and method of analysis used since a variety of glycosides, which are chemically similar to the cardioactive glycosides but without or with fewer cardiac effects, may be incorrectly recognized as digoxin by the test, giving misleading results.
American Psychological Association (APA)
Negroni, Maria Silvia& Marengo, Arianna& Caruso, Donatella& Tayar, Alessandro& Rubiolo, Patrizia& Giavarini, Flavio…[et al.]. 2019. A Case Report of Accidental Intoxication following Ingestion of Foxglove Confused with Borage: High Digoxinemia without Major Complications. Case Reports in Cardiology،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1134098
Modern Language Association (MLA)
Negroni, Maria Silvia…[et al.]. A Case Report of Accidental Intoxication following Ingestion of Foxglove Confused with Borage: High Digoxinemia without Major Complications. Case Reports in Cardiology No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1134098
American Medical Association (AMA)
Negroni, Maria Silvia& Marengo, Arianna& Caruso, Donatella& Tayar, Alessandro& Rubiolo, Patrizia& Giavarini, Flavio…[et al.]. A Case Report of Accidental Intoxication following Ingestion of Foxglove Confused with Borage: High Digoxinemia without Major Complications. Case Reports in Cardiology. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1134098
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1134098