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α4β7 Integrin Antagonist Vedolizumab for the Treatment of Refractory Ileitis
Joint Authors
Filip, Rafał S.
Paluszkiewicz, Piotr
Goliat, Błażej
Dziechciaż, Małgorzata
Dąbrowski, Piotr
Osuchowski, Michał
Source
Case Reports in Gastrointestinal Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-04-22
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background and Aims.
Ulcerative colitis (UC) is a superficial diffuse inflammation restricted to the colon and rectum.
Inflammation within the small bowel may occur several years after a pancolectomy.
The pathogenesis is unknown and seems to be different from Crohn’s disease or other causes of diseases of the small intestine, but an association with colectomy due to UC is very likely.
Methods and Results.
We describe the case of a patient with a probable diagnosis of pan-UC accompanied by Sjögren’s syndrome and partial IgA deficiency, who developed enteritis after a restorative pancolectomy.
For induction and maintenance of remission, the patient was successfully treated with mycofenolate mofetil (MMF) and vedolizumab (VDZ).
Conclusions.
We suggest that a previously refractory to standard therapy UC-related enteritis can be treated with combination MMF and VDZ.
American Psychological Association (APA)
Filip, Rafał S.& Goliat, Błażej& Dziechciaż, Małgorzata& Dąbrowski, Piotr& Osuchowski, Michał& Paluszkiewicz, Piotr. 2019. α4β7 Integrin Antagonist Vedolizumab for the Treatment of Refractory Ileitis. Case Reports in Gastrointestinal Medicine،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1136151
Modern Language Association (MLA)
Filip, Rafał S.…[et al.]. α4β7 Integrin Antagonist Vedolizumab for the Treatment of Refractory Ileitis. Case Reports in Gastrointestinal Medicine No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1136151
American Medical Association (AMA)
Filip, Rafał S.& Goliat, Błażej& Dziechciaż, Małgorzata& Dąbrowski, Piotr& Osuchowski, Michał& Paluszkiewicz, Piotr. α4β7 Integrin Antagonist Vedolizumab for the Treatment of Refractory Ileitis. Case Reports in Gastrointestinal Medicine. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1136151
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1136151