A Rare Case of HHV-8 Associated Hemophagocytic Lymphohistiocytosis in a Stable HIV Patient
Joint Authors
Osakwe, Nonso
Johnson, Diane
Klein, Natalie
Azim, Dalia Abdel
Source
Case Reports in Infectious Diseases
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-04-28
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Background.
Hemophagocytic lymphohistiocytosis (HLH) is a rare condition associated with viral infections including HIV.
Cases have been reported mainly in advanced HIV/AIDS.
This is a rare case that reports HLH associated with human herpes virus-8 (HHV-8) associated multicentric Castleman disease in a stable HIV patient.
Case Presentation.
A 70-year-old Asian male patient with history of stable HIV on medications with CD 4 cell count above 200 presented with cough and fever and was initially treated for pneumonia as an outpatient.
Persisting symptoms prompted presentation to the hospital.
The patient was found to have anemia which persisted despite repeated transfusion of packed red cells.
A bone marrow biopsy to investigate anemia revealed hemophagocytosis.
A CT scan revealed multiple enlarged lymph nodes and hepatosplenomegaly.
An excisional lymph node biopsy revealed HHV-8 associated multicentric Castleman disease.
The patient deteriorated despite initiation of treatment.
Conclusion.
HLH can occur at any stage of HIV, rapid diagnosis to identify possible underlying reactive infectious etiology and prompt initiation of treatment is crucial to survival.
American Psychological Association (APA)
Osakwe, Nonso& Johnson, Diane& Klein, Natalie& Azim, Dalia Abdel. 2019. A Rare Case of HHV-8 Associated Hemophagocytic Lymphohistiocytosis in a Stable HIV Patient. Case Reports in Infectious Diseases،Vol. 2019, no. 2019, pp.1-3.
https://search.emarefa.net/detail/BIM-1136966
Modern Language Association (MLA)
Osakwe, Nonso…[et al.]. A Rare Case of HHV-8 Associated Hemophagocytic Lymphohistiocytosis in a Stable HIV Patient. Case Reports in Infectious Diseases No. 2019 (2019), pp.1-3.
https://search.emarefa.net/detail/BIM-1136966
American Medical Association (AMA)
Osakwe, Nonso& Johnson, Diane& Klein, Natalie& Azim, Dalia Abdel. A Rare Case of HHV-8 Associated Hemophagocytic Lymphohistiocytosis in a Stable HIV Patient. Case Reports in Infectious Diseases. 2019. Vol. 2019, no. 2019, pp.1-3.
https://search.emarefa.net/detail/BIM-1136966
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1136966