Cerebral Venous Thrombosis as Rare Presentation of Herpes Simplex Virus Encephalitis
Joint Authors
Sargento-Freitas, João
Leite, José
Ribeiro, Ana
Gonçalves, Diana
Trindade, Luís
Duque, Victor
Source
Case Reports in Infectious Diseases
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-01-17
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Herpes simplex virus 1 is a prevalent neurotropic pathogen that infects and establishes latency in peripheral sensory neurons.
It can migrate into the central nervous system and cause encephalitis.
The association between herpes simplex virus encephalitis and cerebral venous thrombosis is rare, with a very limited number of case reports described in the literature, despite the recognized thrombogenic effects of the virus.
A 44-year-old man was brought to the emergency department with generalized tonic-clonic seizures requiring sedation and ventilation to control it.
Initial brain computed tomography revealed cortical and subcortical edema on the left frontal lobe, and a subsequent contrast-enhanced exam showed absence of venous flow over the anterior half of the superior sagittal sinus.
Cerebrospinal fluid polymerase chain reaction was positive for herpes simplex virus type 1, and the patient was started on acyclovir and anticoagulation, with clinical improvement.
Acyclovir administration was maintained for 14 days and oral anticoagulation for one year, with no recurrence of thrombotic events or other complications.
A well-timed treatment has a validated prognostic impact on herpes simplex encephalitis, making early recognition of its clinical aspects of main importance.
American Psychological Association (APA)
Leite, José& Ribeiro, Ana& Gonçalves, Diana& Sargento-Freitas, João& Trindade, Luís& Duque, Victor. 2019. Cerebral Venous Thrombosis as Rare Presentation of Herpes Simplex Virus Encephalitis. Case Reports in Infectious Diseases،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1137130
Modern Language Association (MLA)
Leite, José…[et al.]. Cerebral Venous Thrombosis as Rare Presentation of Herpes Simplex Virus Encephalitis. Case Reports in Infectious Diseases No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1137130
American Medical Association (AMA)
Leite, José& Ribeiro, Ana& Gonçalves, Diana& Sargento-Freitas, João& Trindade, Luís& Duque, Victor. Cerebral Venous Thrombosis as Rare Presentation of Herpes Simplex Virus Encephalitis. Case Reports in Infectious Diseases. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1137130
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1137130