Metastatic Crohn’s Disease: An Approach to an Uncommon but Important Cutaneous Disorder
Joint Authors
Aberumand, Babak
Howard, Jessica
Howard, John
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-01-03
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
To provide physicians with a clinical approach to metastatic Crohn’s disease (MCD).
Main Message.
Metastatic Crohn’s disease, defined as skin lesions present in areas noncontiguous with the gastrointestinal tract, is the rarest cutaneous manifestation of Crohn’s disease.
MCD lesions vary in morphology and can arise anywhere on the skin.
MCD presents equally in both sexes and across age groups.
Cutaneous findings may precede, develop concurrently with, or follow gastrointestinal involvement.
A detailed history and thorough physical examination including a full-skin exam may help to exclude other dermatoses, as MCD can mimic other common disorders.
A biopsy is required for a definitive diagnosis.
Treatment options for MCD remain underwhelming due to the lack of randomized control studies and varying responses of reported therapeutic methods.
Topical, intralesional, and systemic corticosteroids, antibiotics, traditional immunosuppressants, and surgery have shown mixed results.
Recently, biologics have shown promise, even with refractory cases of MCD.
Conclusion.
MCD is an important cutaneous manifestation of this inflammatory disorder.
Although a rare entity, early recognition can provide opportunity for successful therapeutic intervention.
American Psychological Association (APA)
Aberumand, Babak& Howard, Jessica& Howard, John. 2017. Metastatic Crohn’s Disease: An Approach to an Uncommon but Important Cutaneous Disorder. BioMed Research International،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1138951
Modern Language Association (MLA)
Aberumand, Babak…[et al.]. Metastatic Crohn’s Disease: An Approach to an Uncommon but Important Cutaneous Disorder. BioMed Research International No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1138951
American Medical Association (AMA)
Aberumand, Babak& Howard, Jessica& Howard, John. Metastatic Crohn’s Disease: An Approach to an Uncommon but Important Cutaneous Disorder. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1138951
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1138951