Cerebral Reorganization in Subacute Stroke Survivors after Virtual Reality-Based Training: A Preliminary Study
Joint Authors
Zhou, Shu-Feng
Lo, Wai Leung
Lin, Qiang
Xiao, Xiang
Huang, Dong-Feng
Shi, Xin-chong
Cates, Ryan S.
Mao, Yurong
Li, Le
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-06-28
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
Functional magnetic resonance imaging (fMRI) is a promising method for quantifying brain recovery and investigating the intervention-induced changes in corticomotor excitability after stroke.
This study aimed to evaluate cortical reorganization subsequent to virtual reality-enhanced treadmill (VRET) training in subacute stroke survivors.
Methods.
Eight participants with ischemic stroke underwent VRET for 5 sections per week and for 3 weeks.
fMRI was conducted to quantify the activity of selected brain regions when the subject performed ankle dorsiflexion.
Gait speed and clinical scales were also measured before and after intervention.
Results.
Increased activation in the primary sensorimotor cortex of the lesioned hemisphere and supplementary motor areas of both sides for the paretic foot (p<0.01) was observed postintervention.
Statistically significant improvements were observed in gait velocity (p<0.05).
The change in voxel counts in the primary sensorimotor cortex of the lesioned hemisphere is significantly correlated with improvement of 10 m walk time after VRET (r=−0.719).
Conclusions.
We observed improved walking and increased activation in cortical regions of stroke survivors after VRET training.
Moreover, the cortical recruitment was associated with better walking function.
Our study suggests that cortical networks could be a site of plasticity, and their recruitment may be one mechanism of training-induced recovery of gait function in stroke.
This trial is registered with ChiCTR-IOC-15006064.
American Psychological Association (APA)
Xiao, Xiang& Lin, Qiang& Lo, Wai Leung& Mao, Yurong& Shi, Xin-chong& Cates, Ryan S.…[et al.]. 2017. Cerebral Reorganization in Subacute Stroke Survivors after Virtual Reality-Based Training: A Preliminary Study. Behavioural Neurology،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1139782
Modern Language Association (MLA)
Xiao, Xiang…[et al.]. Cerebral Reorganization in Subacute Stroke Survivors after Virtual Reality-Based Training: A Preliminary Study. Behavioural Neurology No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1139782
American Medical Association (AMA)
Xiao, Xiang& Lin, Qiang& Lo, Wai Leung& Mao, Yurong& Shi, Xin-chong& Cates, Ryan S.…[et al.]. Cerebral Reorganization in Subacute Stroke Survivors after Virtual Reality-Based Training: A Preliminary Study. Behavioural Neurology. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1139782
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1139782