Clinical Applications of Contrast-Enhanced Perfusion MRI Techniques in Gliomas: Recent Advances and Current Challenges
Joint Authors
Liu, Gang
Zhang, Junfeng
Liu, Heng
Tong, Haipeng
Wang, Sumei
Yang, Yizeng
Zhang, Weiguo
Source
Contrast Media & Molecular Imaging
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-27, 27 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-03-20
Country of Publication
Egypt
No. of Pages
27
Main Subjects
Abstract EN
Gliomas possess complex and heterogeneous vasculatures with abnormal hemodynamics.
Despite considerable advances in diagnostic and therapeutic techniques for improving tumor management and patient care in recent years, the prognosis of malignant gliomas remains dismal.
Perfusion-weighted magnetic resonance imaging techniques that could noninvasively provide superior information on vascular functionality have attracted much attention for evaluating brain tumors.
However, nonconsensus imaging protocols and postprocessing analysis among different institutions impede their integration into standard-of-care imaging in clinic.
And there have been very few studies providing a comprehensive evidence-based and systematic summary.
This review first outlines the status of glioma theranostics and tumor-associated vascular pathology and then presents an overview of the principles of dynamic contrast-enhanced MRI (DCE-MRI) and dynamic susceptibility contrast-MRI (DSC-MRI), with emphasis on their recent clinical applications in gliomas including tumor grading, identification of molecular characteristics, differentiation of glioma from other brain tumors, treatment response assessment, and predicting prognosis.
Current challenges and future perspectives are also highlighted.
American Psychological Association (APA)
Zhang, Junfeng& Liu, Heng& Tong, Haipeng& Wang, Sumei& Yang, Yizeng& Liu, Gang…[et al.]. 2017. Clinical Applications of Contrast-Enhanced Perfusion MRI Techniques in Gliomas: Recent Advances and Current Challenges. Contrast Media & Molecular Imaging،Vol. 2017, no. 2017, pp.1-27.
https://search.emarefa.net/detail/BIM-1141828
Modern Language Association (MLA)
Zhang, Junfeng…[et al.]. Clinical Applications of Contrast-Enhanced Perfusion MRI Techniques in Gliomas: Recent Advances and Current Challenges. Contrast Media & Molecular Imaging No. 2017 (2017), pp.1-27.
https://search.emarefa.net/detail/BIM-1141828
American Medical Association (AMA)
Zhang, Junfeng& Liu, Heng& Tong, Haipeng& Wang, Sumei& Yang, Yizeng& Liu, Gang…[et al.]. Clinical Applications of Contrast-Enhanced Perfusion MRI Techniques in Gliomas: Recent Advances and Current Challenges. Contrast Media & Molecular Imaging. 2017. Vol. 2017, no. 2017, pp.1-27.
https://search.emarefa.net/detail/BIM-1141828
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1141828