A Case of 14-Year-Old Male with Fibroma of Tendon Sheath of the Hand with Novel Chromosomal Translocation 4;10
Joint Authors
Fitzhugh, Valerie A.
Ahmed, Irfan
Rubinstein, Aaron
Vosbikian, Michael
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-09-17
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Fibroma of tendon sheath (FTS) is an uncommonly encountered soft tissue mass, which is morphologically distinct from the more commonly seen giant cell tumor of tendon sheath (GCTTS).
Initially described in 1936, FTS is typically a slow growing, painless, firm mass with a predilection for the upper extremity, frequently involving the hand.
Cases of associated triggering or compression neuropathies have been described when underlying tendons or nerves are affected.
Currently, the literature on FTS is sparse and largely limited to case reports.
More recently, few reports of cytogenetic analysis on FTS have been reported in the literature.
Cellular and chromosomal analysis of FTS tissue revealed chromosomal translocations with yet unknown clinical significance.
Here, we present a case report of FTS in a 14-year-old male with a painless enlarging mass on the palmar side of the left hand treated by excision.
Subsequent karyotypic analysis revealed a chromosomal translocation t(4;10) (p16;q24), add (10)(q22)[24].
To our knowledge, this is the first description of this chromosomal aberration in the literature.
American Psychological Association (APA)
Rubinstein, Aaron& Fitzhugh, Valerie A.& Ahmed, Irfan& Vosbikian, Michael. 2019. A Case of 14-Year-Old Male with Fibroma of Tendon Sheath of the Hand with Novel Chromosomal Translocation 4;10. Case Reports in Orthopedics،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1142583
Modern Language Association (MLA)
Rubinstein, Aaron…[et al.]. A Case of 14-Year-Old Male with Fibroma of Tendon Sheath of the Hand with Novel Chromosomal Translocation 4;10. Case Reports in Orthopedics No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1142583
American Medical Association (AMA)
Rubinstein, Aaron& Fitzhugh, Valerie A.& Ahmed, Irfan& Vosbikian, Michael. A Case of 14-Year-Old Male with Fibroma of Tendon Sheath of the Hand with Novel Chromosomal Translocation 4;10. Case Reports in Orthopedics. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1142583
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1142583