A Case of Euthyroid Graves’ Ophthalmopathy in a Patient Sero-Negative for TSH Receptor Autoantibody
Joint Authors
Hotta, Asami
Tanaka, Tomohiro
Kato, Haruka
Kakoi, Shota
Shimizu, Yuki
Hasegawa, Chie
Hayakawa, Akiko
Yasuda, Satoshi
Ogawa, Kento
Ito, Shunsuke
Ohguchi, Hideomi
Yagi, Takashi
Koyama, Hiroyuki
Kawamura, Mihoko
Sugitani, Kazuhiko
Ogura, Yuichiro
Imaeda, Kenro
Joh, Takashi
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-06-13
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
We report of a case of Graves’ ophthalmopathy presented solely with symptoms of the eyes with normal thyroid function tests and negative immunoreactive TSH receptor autoantibody.
40-year-old male was referred to our hospital due to 2-month history of ocular focusing deficit without any signs or symptoms of hyper- or hypothyroidism.
Serum thyroid function tests and 99mTc uptake were both within the normal range.
Anti-thyroid autoantibodies were all negative except for the cell-based assay for serum TSH receptor stimulating activity.
Since orbital CT scan and MRI gave typical results compatible with Graves’ ophthalmopathy, we treated the patients with corticosteroid pulse therapy and orbital radiation therapy, leading to a partial improvement of the symptoms.
This case gives insights into the potential pathophysiologic mechanism underlying Graves’ ophthalmopathy and casts light upon the difficulties of establishing the diagnosis in a euthyroid case with minimal positive results for anti-thyroid autoantibodies.
American Psychological Association (APA)
Hotta, Asami& Tanaka, Tomohiro& Kato, Haruka& Kakoi, Shota& Shimizu, Yuki& Hasegawa, Chie…[et al.]. 2018. A Case of Euthyroid Graves’ Ophthalmopathy in a Patient Sero-Negative for TSH Receptor Autoantibody. Case Reports in Endocrinology،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1142889
Modern Language Association (MLA)
Hotta, Asami…[et al.]. A Case of Euthyroid Graves’ Ophthalmopathy in a Patient Sero-Negative for TSH Receptor Autoantibody. Case Reports in Endocrinology No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1142889
American Medical Association (AMA)
Hotta, Asami& Tanaka, Tomohiro& Kato, Haruka& Kakoi, Shota& Shimizu, Yuki& Hasegawa, Chie…[et al.]. A Case of Euthyroid Graves’ Ophthalmopathy in a Patient Sero-Negative for TSH Receptor Autoantibody. Case Reports in Endocrinology. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1142889
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1142889