Long-Term Remission of a Spinal Atypical Teratoid Rhabdoid Tumor in Response to Intensive Multimodal Therapy
Joint Authors
Al-Maghrabi, Jaudah
Al-Maghrabi, Haneen
Refai, Fahd
Al Trabolsi, Hassan
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-10-13
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Atypical teratoid rhabdoid tumors (ATRTs) are rare and aggressive central nervous system tumors that infrequently arise in spinal locations in young children.
Provided clinical and diagnostic suspicion is high, the histopathological diagnosis is relatively straightforward to secure by testing for the characteristic loss of the tumor suppressor protein SMARCB1/INI1.
Here, we describe a case of thoracic spinal ATRT in a three-year-old boy that showed characteristic aggressive progression until managed with intensive multimodal therapy to achieve durable long-term remission.
In doing so, we review the histopathological features, management, and current advances in molecular biology that hold promise for personalized ATRT therapy.
American Psychological Association (APA)
Refai, Fahd& Al-Maghrabi, Haneen& Al Trabolsi, Hassan& Al-Maghrabi, Jaudah. 2019. Long-Term Remission of a Spinal Atypical Teratoid Rhabdoid Tumor in Response to Intensive Multimodal Therapy. Case Reports in Pediatrics،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1143685
Modern Language Association (MLA)
Refai, Fahd…[et al.]. Long-Term Remission of a Spinal Atypical Teratoid Rhabdoid Tumor in Response to Intensive Multimodal Therapy. Case Reports in Pediatrics No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1143685
American Medical Association (AMA)
Refai, Fahd& Al-Maghrabi, Haneen& Al Trabolsi, Hassan& Al-Maghrabi, Jaudah. Long-Term Remission of a Spinal Atypical Teratoid Rhabdoid Tumor in Response to Intensive Multimodal Therapy. Case Reports in Pediatrics. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1143685
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1143685