E. coli Sepsis: Red Flag for Colon Carcinoma—A Case Report and Review of the Literature
Joint Authors
Patel, Hiren
Shaikh, Sohail
Tabassum, Seme
Source
Case Reports in Gastrointestinal Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-06-13
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
We present an atypical case of newly diagnosed colon cancer and provide insight into the infectious predispositions of E.
coli bacteremia to the development of colon adenocarcinoma.
A 66-year-old female was admitted to the hospital with one-week symptoms of subjective fevers, chills, and lower back pain.
Upon initial evaluation, her temperature was 101 degrees Fahrenheit with a white count of 12,000 K/mm3.
Initial septic workup was positive for E.
coli bacteremia.
The patient was started on Aztreonam.
Repeat blood culture 48 hours later was negative for any growth.
However, later during hospital stay blood culture was repeated due to SIRS, which was positive again for E.
coli.
CT scan of the chest/abdomen/pelvis with contrast revealed no signs of colitis.
Without clear etiology for recurrent E.
coli bacteremia ultimately colonoscopy was performed which showed an ulcerated mass in the cecum.
Biopsy showed moderately differentiated adenocarcinoma.
E.
coli strains B2 and D produce cyclomodulin toxins as part of their virulence, which interferes with the cell cycle regulation, promoting chromosomal instability, and increasing susceptibility to cancer.
In patients with recurrent E.
coli bacteremia with an unknown source, colonoscopy should be done to look for colon cancer.
American Psychological Association (APA)
Patel, Hiren& Tabassum, Seme& Shaikh, Sohail. 2017. E. coli Sepsis: Red Flag for Colon Carcinoma—A Case Report and Review of the Literature. Case Reports in Gastrointestinal Medicine،Vol. 2017, no. 2017, pp.1-3.
https://search.emarefa.net/detail/BIM-1145469
Modern Language Association (MLA)
Patel, Hiren…[et al.]. E. coli Sepsis: Red Flag for Colon Carcinoma—A Case Report and Review of the Literature. Case Reports in Gastrointestinal Medicine No. 2017 (2017), pp.1-3.
https://search.emarefa.net/detail/BIM-1145469
American Medical Association (AMA)
Patel, Hiren& Tabassum, Seme& Shaikh, Sohail. E. coli Sepsis: Red Flag for Colon Carcinoma—A Case Report and Review of the Literature. Case Reports in Gastrointestinal Medicine. 2017. Vol. 2017, no. 2017, pp.1-3.
https://search.emarefa.net/detail/BIM-1145469
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1145469