Epithelial Ovarian Carcinoma Associated with Metastases to Central Nervous System: Two Case Reports
Joint Authors
Sato, Yuichiro
Sameshima, Hiroshi
Kawagoe, Yasuyuki
Nakayama, Tetsuo
Matuzawa, Satoshi
Fukushima, Kazuko
Onishi, Junji
Nagai, Kimihiro
Source
Case Reports in Obstetrics and Gynecology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-10-02
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
We experienced two rare cases of metastases to the central nervous system (cerebral and leptomeningeal metastases) from primary epithelial ovarian carcinoma.
The first case was a 55-year-old woman who developed carcinomatous meningitis while on chemotherapy for ovarian cancer stage IIIC.
Cytological analysis confirmed carcinomatous cells of ovarian origin in the cerebrospinal fluid.
Magnetic resonance imaging demonstrated abnormal hyperintensity in the cerebral sulci on fluid attenuated inversion recovery (FLAIR) sequence with enhanced gadolinium indicating leptomeningeal metastases.
Her consciousness rapidly declined and she died 42 days after diagnosis.
The second case was a 63-year-old woman who underwent surgery for ovarian cancer and who was diagnosed as stage IA.
Thirty-eight months after surgery, she developed weakness of the left hand and headaches.
A CT scan revealed metastases to the right cerebrum and she was treated with surgical resection followed by radiotherapy.
Five months after resection, she developed ileus caused by multiple relapses in the pelvis.
Despite chemotherapy, her performance status declined and she died nine months after the resection.
Both cases were rare because the first case was isolated leptomeningeal metastases, and the second case was confirmed relapse site in the cerebrum due to neurological symptoms despite her early clinical stage.
American Psychological Association (APA)
Kawagoe, Yasuyuki& Nakayama, Tetsuo& Matuzawa, Satoshi& Fukushima, Kazuko& Onishi, Junji& Sato, Yuichiro…[et al.]. 2018. Epithelial Ovarian Carcinoma Associated with Metastases to Central Nervous System: Two Case Reports. Case Reports in Obstetrics and Gynecology،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1145719
Modern Language Association (MLA)
Kawagoe, Yasuyuki…[et al.]. Epithelial Ovarian Carcinoma Associated with Metastases to Central Nervous System: Two Case Reports. Case Reports in Obstetrics and Gynecology No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1145719
American Medical Association (AMA)
Kawagoe, Yasuyuki& Nakayama, Tetsuo& Matuzawa, Satoshi& Fukushima, Kazuko& Onishi, Junji& Sato, Yuichiro…[et al.]. Epithelial Ovarian Carcinoma Associated with Metastases to Central Nervous System: Two Case Reports. Case Reports in Obstetrics and Gynecology. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1145719
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1145719