Macroglossia in Beckwith-Wiedemann Syndrome Is Attributed to Skeletal Muscle Hyperplasia

Joint Authors

Daa, Tsutomu
Oyama, Yuzo
Nishida, Haruto
Kawano, Kenji
Ihara, Kenji
Kobayashi, Osamu

Source

Case Reports in Dentistry

Issue

Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2020-11-02

Country of Publication

Egypt

No. of Pages

6

Main Subjects

Dental

Abstract EN

Macroglossia is a common feature in patients with Beckwith-Wiedemann syndrome (BWS).

The underlying cause of macroglossia in BWS remains unknown, and further histological studies are required to uncover its etiology.

We present the case of a 5-year-old girl who was diagnosed with BWS and underwent partial tongue resection for difficulties in articulation and aesthetics.

The keyhole-shaped partial resection revealed a harder posterior side than the anterior.

Microscopically, the posterior side consisted of dense subepithelial eosinophilic areas composed of an abundance of tightly packed skeletal muscle fibers that were arranged in a fascicular or storiform pattern.

BWS-associated macroglossia results from skeletal muscle hyperplasia, consistent with true macroglossia.

Therefore, tongue resection may be beneficial for such patients.

Further studies are required to develop personalized surgical interventions for each patient with BWS.

American Psychological Association (APA)

Oyama, Yuzo& Nishida, Haruto& Kobayashi, Osamu& Kawano, Kenji& Ihara, Kenji& Daa, Tsutomu. 2020. Macroglossia in Beckwith-Wiedemann Syndrome Is Attributed to Skeletal Muscle Hyperplasia. Case Reports in Dentistry،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1146753

Modern Language Association (MLA)

Kobayashi, Osamu…[et al.]. Macroglossia in Beckwith-Wiedemann Syndrome Is Attributed to Skeletal Muscle Hyperplasia. Case Reports in Dentistry No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1146753

American Medical Association (AMA)

Oyama, Yuzo& Nishida, Haruto& Kobayashi, Osamu& Kawano, Kenji& Ihara, Kenji& Daa, Tsutomu. Macroglossia in Beckwith-Wiedemann Syndrome Is Attributed to Skeletal Muscle Hyperplasia. Case Reports in Dentistry. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1146753

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1146753