Acute Brucellosis and Cirrhosis: The Triggering Event of Fatal Liver Decompensation

Joint Authors

Kosmidou, Maria
Klouras, Eleftherios
Rapti, Iro
Filippas-Ntekouan, Sebastien
Milionis, Haralampos

Source

Case Reports in Hepatology

Issue

Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-4, 4 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2020-12-22

Country of Publication

Egypt

No. of Pages

4

Main Subjects

Diseases

Abstract EN

Cirrhotic patients are known to be particularly susceptible to infectious complications that may vary according to regional endemic patterns.

Brucellosis, a common zoonosis with worldwide distribution, exhibits a predilection for the reticuloendothelial system and thus resulting in hepatic involvement.

We describe three cirrhotic patients in whom acute brucellosis and/or its treatment served as the triggering factor of hepatic decompensation, with deleterious effects.

The patients suffered from alcoholic cirrhosis and culture-proven brucellosis.

All patients came from an area endemic to brucellosis.

The first patient exhibited a relapsing brucellosis course with progressive deterioration of his fragile liver function.

The second patient progressed rapidly to jaundice, possibly partly attributed to antibiotic pharmacotoxicity, and died during liver transplantation.

The third patient eventually succumbed to diffuse intravascular coagulation.

Brucellosis can be a triggering event of fatal liver decompensation in cirrhotic patients.

Enhancing health literacy of the patients, particularly in endemic areas, is of paramount importance for prevention of exposure to similar pathogens.

American Psychological Association (APA)

Kosmidou, Maria& Klouras, Eleftherios& Rapti, Iro& Filippas-Ntekouan, Sebastien& Milionis, Haralampos. 2020. Acute Brucellosis and Cirrhosis: The Triggering Event of Fatal Liver Decompensation. Case Reports in Hepatology،Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1147972

Modern Language Association (MLA)

Kosmidou, Maria…[et al.]. Acute Brucellosis and Cirrhosis: The Triggering Event of Fatal Liver Decompensation. Case Reports in Hepatology No. 2020 (2020), pp.1-4.
https://search.emarefa.net/detail/BIM-1147972

American Medical Association (AMA)

Kosmidou, Maria& Klouras, Eleftherios& Rapti, Iro& Filippas-Ntekouan, Sebastien& Milionis, Haralampos. Acute Brucellosis and Cirrhosis: The Triggering Event of Fatal Liver Decompensation. Case Reports in Hepatology. 2020. Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1147972

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1147972