Bilateral Ureteral Stenosis with Hydronephrosis as First Manifestation of Granulomatosis with Polyangiitis (Wegener’s Granulomatosis): A Case Report and Review of the Literature
Joint Authors
Suillot, Joelle
Bollmann, Jürg
Rotman, Samuel
Descombes, Eric
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-12-23
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Ureteral stenosis is a rare manifestation of granulomatosis with polyangiitis (formerly known as Wegener’s granulomatosis).
We report the case of a 76-year-old woman with progressive renal failure in which bilateral hydronephrosis due to ureteral stenosis was the first manifestation of the disease.
Our patient also had renal involvement with pauci-immune crescentic glomerulonephritis associated with high titers of anti-proteinase 3 c-ANCAs, but no involvement of the upper or lower respiratory tract.
The hydronephrosis and renal function rapidly improved under immunosuppressive therapy with high-dose corticosteroids and intravenous pulse cyclophosphamide.
We reviewed the literature and found only ten other reported cases of granulomatosis with polyangiitis/Wegener’s granulomatosis and intrinsic ureteral stenosis: in two cases, the presenting clinical manifestation was unilateral hydronephrosis and in only two others was the hydronephrosis bilateral, but this complication developed during a relapse of the disease.
This case emphasizes the importance of including ANCA-related vasculitis in the differential diagnosis of unusual cases of unilateral or bilateral ureteral stenosis.
American Psychological Association (APA)
Suillot, Joelle& Bollmann, Jürg& Rotman, Samuel& Descombes, Eric. 2020. Bilateral Ureteral Stenosis with Hydronephrosis as First Manifestation of Granulomatosis with Polyangiitis (Wegener’s Granulomatosis): A Case Report and Review of the Literature. Case Reports in Nephrology،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1148781
Modern Language Association (MLA)
Suillot, Joelle…[et al.]. Bilateral Ureteral Stenosis with Hydronephrosis as First Manifestation of Granulomatosis with Polyangiitis (Wegener’s Granulomatosis): A Case Report and Review of the Literature. Case Reports in Nephrology No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1148781
American Medical Association (AMA)
Suillot, Joelle& Bollmann, Jürg& Rotman, Samuel& Descombes, Eric. Bilateral Ureteral Stenosis with Hydronephrosis as First Manifestation of Granulomatosis with Polyangiitis (Wegener’s Granulomatosis): A Case Report and Review of the Literature. Case Reports in Nephrology. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1148781
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1148781