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Possible Correlation between Hypomelanosis of Ito and Wilms’ Tumor
Joint Authors
Bello-Germino, Daniella
Chhin, Rasmey
Tran, Thu
Vasylyeva, Tetyana L.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-16
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Hypomelanosis of Ito is a neurocutaneous disorder characterized by skin manifestations in a characteristic pattern associated with musculoskeletal and central nervous system symptoms.
Our patient was diagnosed with Wilms’ tumor stage I at age two and was also found to have distinct streaked areas of skin hyper- and hypopigmentation suggestive of Hypomelanosis of Ito.
We believe that our patient’s clinical diagnoses of Hypomelanosis of Ito and Wilms’ tumor are interlinked.
The connecting factor is yet to be identified.
Our patient does not have a deletion of 11p13 associated with a defect in WT1, the Wilms’ tumor suppressor gene.
As such, it is quite possible that what made her more susceptible to the development of Wilms’ tumor was her Hypomelanosis of Ito, which is implicated in a number of other organ dysfunctions.
American Psychological Association (APA)
Bello-Germino, Daniella& Chhin, Rasmey& Tran, Thu& Vasylyeva, Tetyana L.. 2018. Possible Correlation between Hypomelanosis of Ito and Wilms’ Tumor. Case Reports in Pediatrics،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1149141
Modern Language Association (MLA)
Bello-Germino, Daniella…[et al.]. Possible Correlation between Hypomelanosis of Ito and Wilms’ Tumor. Case Reports in Pediatrics No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1149141
American Medical Association (AMA)
Bello-Germino, Daniella& Chhin, Rasmey& Tran, Thu& Vasylyeva, Tetyana L.. Possible Correlation between Hypomelanosis of Ito and Wilms’ Tumor. Case Reports in Pediatrics. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1149141
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1149141