Diagnosis of Systemic Lupus Erythematosus in a Polynesian Male with a History of Rheumatic Fever: A Case Report and Literature Review
Joint Authors
Kurahara, David
Yamamoto, Kara
Diaz, Charyse
Lim, Matthew A.
Liu, Chloe A.
Miwa, Chloe S.
Tokunaga, Darcy
Hamamura, Faith D.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-12-30
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
The presence of rheumatic heart disease (RHD) and systemic lupus erythematosus (SLE) has rarely been described in one patient.
This report describes an adolescent Polynesian male with RHD who developed SLE years later.
Initially, he fulfilled modified Jones criteria for rheumatic fever with aortic insufficiency, transient arthritis, elevated streptococcal titers, and a high erythrocyte sedimentation rate with a negative antinuclear antibody (ANA).
He responded well to nonsteroidal anti-inflammatory and penicillin prophylaxis, which supported the diagnosis of rheumatic fever.
Five years after his RHD diagnosis, he developed pancreatitis with glomerulonephritis, nephrosis, and pancytopenia.
In addition, laboratory results revealed that he had multiple autoantibodies: anti-Sm and extremely elevated anti-dsDNA and ANA, fulfilling diagnostic criteria for SLE.
The patient was treated, and he responded to pulse steroids followed by oral steroid therapy.
To our knowledge, there are no known reported cases of a patient who was diagnosed with both RHD and SLE and met the clinical criteria for both diseases.
The rarity of this concurrent disease process in one patient suggests a possible overlap in humoral immunity toward self-antigens as well as ethnic variability that increases predisposition to rheumatologic diseases.
American Psychological Association (APA)
Diaz, Charyse& Lim, Matthew A.& Liu, Chloe A.& Miwa, Chloe S.& Tokunaga, Darcy& Hamamura, Faith D.…[et al.]. 2018. Diagnosis of Systemic Lupus Erythematosus in a Polynesian Male with a History of Rheumatic Fever: A Case Report and Literature Review. Case Reports in Pediatrics،Vol. 2018, no. 2018, pp.1-3.
https://search.emarefa.net/detail/BIM-1149248
Modern Language Association (MLA)
Diaz, Charyse…[et al.]. Diagnosis of Systemic Lupus Erythematosus in a Polynesian Male with a History of Rheumatic Fever: A Case Report and Literature Review. Case Reports in Pediatrics No. 2018 (2018), pp.1-3.
https://search.emarefa.net/detail/BIM-1149248
American Medical Association (AMA)
Diaz, Charyse& Lim, Matthew A.& Liu, Chloe A.& Miwa, Chloe S.& Tokunaga, Darcy& Hamamura, Faith D.…[et al.]. Diagnosis of Systemic Lupus Erythematosus in a Polynesian Male with a History of Rheumatic Fever: A Case Report and Literature Review. Case Reports in Pediatrics. 2018. Vol. 2018, no. 2018, pp.1-3.
https://search.emarefa.net/detail/BIM-1149248
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1149248