Coexistent Non–Small Cell Carcinoma and Small Cell Carcinoma in a Patient Presenting with Hyponatremia
Joint Authors
Panchabhai, Tanmay S.
Biswas Roy, Sreeja
Ross, Mitchell D.
Patil, Pradnya D.
Huang, Jasmine L.
Thawani, Nitika
Drosten, Ralph
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-02-20
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Despite recent advances in screening methods, lung cancer remains the leading cause of cancer-related deaths worldwide.
By the time lung cancer becomes symptomatic and patients seek treatment, it is often too advanced for curative measures.
Low-dose computed tomography (CT) screening has been shown to reduce mortality in patients at high risk of lung cancer.
We present a 66-year-old man with a 50-pack-year smoking history who had a right upper lobe (RUL) pulmonary nodule and left lower lobe (LLL) consolidation on a screening CT.
He reported a weight loss of 45 pounds over 3 months, had recently been hospitalized for hyponatremia, and was notably cachectic.
A CT of the chest showed a stable LLL mass-like consolidation and a 9 × 21 mm subsolid lesion in the RUL.
Navigational bronchoscopy biopsy of the RUL lesion revealed squamous non–small cell lung cancer (NSCLC).
Endobronchial ultrasound-guided transbronchial needle aspiration of the LLL lesion revealed small cell lung cancer (SCLC).
The final diagnosis was a right-sided Stage I NSCLC (squamous) and a left-sided limited SCLC.
The RUL NSCLC was treated with stereotactic radiation; the LLL SCLC was treated with concurrent chemotherapy and radiation.
In patients with multiple lung nodules, a diagnosis of synchronous multiple primary lung cancers (MPLCs) is crucial, as inadvertent upstaging of patients with MPLC (to T3 and/or T4 tumors) can lead to erroneous staging, inaccurate prognosis, and improper treatment.
Recent advances in the diagnosis of small pulmonary nodules via navigational bronchoscopy and management of these lesions dramatically affect a patient’s overall prognosis.
American Psychological Association (APA)
Ross, Mitchell D.& Biswas Roy, Sreeja& Patil, Pradnya D.& Huang, Jasmine L.& Thawani, Nitika& Drosten, Ralph…[et al.]. 2018. Coexistent Non–Small Cell Carcinoma and Small Cell Carcinoma in a Patient Presenting with Hyponatremia. Case Reports in Pulmonology،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1149443
Modern Language Association (MLA)
Ross, Mitchell D.…[et al.]. Coexistent Non–Small Cell Carcinoma and Small Cell Carcinoma in a Patient Presenting with Hyponatremia. Case Reports in Pulmonology No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1149443
American Medical Association (AMA)
Ross, Mitchell D.& Biswas Roy, Sreeja& Patil, Pradnya D.& Huang, Jasmine L.& Thawani, Nitika& Drosten, Ralph…[et al.]. Coexistent Non–Small Cell Carcinoma and Small Cell Carcinoma in a Patient Presenting with Hyponatremia. Case Reports in Pulmonology. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1149443
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1149443