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Primitive Neuroectodermal Tumor and Wegener’s Granulomatosis of the Kidney: A Curious Combination of Two Rare Entities
Joint Authors
Tretiakova, Maria S.
Parakh, Rugvedita
Parakh, Satyajeet
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-01
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Wegener’s granulomatosis (WG) is characterized by necrotizing polyangiitis involving the respiratory tract and kidneys.
It causes segmental necrotizing glomerulonephritis in the kidneys.
In rare cases, a renal pseudotumor may be seen because of the granulomatous process.
Association of WG with renal malignancy, however, is very uncommon.
We report a case of a patient who presented several years after being treated for WG with malignant hypertension and an infiltrating mass in the right kidney.
The histopathology of radical nephrectomy specimen showed presence of primitive neuroectodermal tumor (PNET).
Association of renal cell carcinoma (RCC) with WG has been documented in a few cases, but PNET in such circumstances has not been reported.
Long-term immunosuppressive treatment is a known risk factor in the development of malignancies, so it is proposed that the occurrence of RCC in WG may have been a side effect of cyclophosphamide treatment.
It is not clear whether the same mechanism for PNET holds true in the present case.
It is important to make a differential diagnosis between true malignancy and pseudotumors in WG as these entities cannot be distinguished based solely on imaging.
We suggest a need to routinely screen the WG patients for increased risk of urologic malignancies.
American Psychological Association (APA)
Parakh, Rugvedita& Parakh, Satyajeet& Tretiakova, Maria S.. 2017. Primitive Neuroectodermal Tumor and Wegener’s Granulomatosis of the Kidney: A Curious Combination of Two Rare Entities. Case Reports in Urology،Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1150501
Modern Language Association (MLA)
Parakh, Rugvedita…[et al.]. Primitive Neuroectodermal Tumor and Wegener’s Granulomatosis of the Kidney: A Curious Combination of Two Rare Entities. Case Reports in Urology No. 2017 (2017), pp.1-4.
https://search.emarefa.net/detail/BIM-1150501
American Medical Association (AMA)
Parakh, Rugvedita& Parakh, Satyajeet& Tretiakova, Maria S.. Primitive Neuroectodermal Tumor and Wegener’s Granulomatosis of the Kidney: A Curious Combination of Two Rare Entities. Case Reports in Urology. 2017. Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1150501
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1150501