Right Ventricular Remodeling and Dysfunction in Obstructive Sleep Apnea: A Systematic Review of the Literature and Meta-Analysis
Joint Authors
Maripov, Abdirashit
Mamazhakypov, Argen
Sartmyrzaeva, Meerim
Akunov, Almaz
Muratali uulu, Kubatbek
Duishobaev, Melis
Cholponbaeva, Meerim
Sydykov, Akylbek
Sarybaev, Akpay
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-07-26
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Background.
Recent studies have reported that obstructive sleep apnea (OSA) patients present alterations in right ventricular (RV) structure and function.
However, large randomized controlled trials evaluating the impact of OSA on the right ventricle are lacking.
Methods.
A comprehensive electronic database (PubMed, Web of Science, and Google Scholar) and reference search up to October 30, 2016, was performed.
A systematic review and meta-analysis were performed to assess RV structure and function in OSA patients based on conventional echocardiography and tissue Doppler imaging.
Results.
Twenty-five studies with 1,503 OSA patients and 796 controls were included in this study.
OSA patients exhibited an increase in RV internal diameter (weighted mean difference (WMD) (95% confidence intervals (CIs)) 2.49 (1.62 to 3.37); p=0.000) and RV wall thickness (WMD (95% CIs) 0.82 (0.51 to 1.13); p=0.000).
Furthermore, OSA patients had a significantly elevated RV myocardial performance index (WMD (95% CI) 0.08 (0.06 to 0.10); p=0.000), decreased RV S’ (WMD (95% CI) −0.95 (−1.59 to −0.32); p=0.003), tricuspid annular plane systolic excursion (WMD (95% CI) −1.76 (−2.73 to −0.78); p=0.000), and RV fractional area change (WMD (95% CI) −3.16 (−5.60 to −0.73); p=0.011).
Conclusion.
OSA patients display RV dilatation, increased wall thickening, and altered RV function.
American Psychological Association (APA)
Maripov, Abdirashit& Mamazhakypov, Argen& Sartmyrzaeva, Meerim& Akunov, Almaz& Muratali uulu, Kubatbek& Duishobaev, Melis…[et al.]. 2017. Right Ventricular Remodeling and Dysfunction in Obstructive Sleep Apnea: A Systematic Review of the Literature and Meta-Analysis. Canadian Respiratory Journal،Vol. 2017, no. 2017, pp.1-13.
https://search.emarefa.net/detail/BIM-1150780
Modern Language Association (MLA)
Maripov, Abdirashit…[et al.]. Right Ventricular Remodeling and Dysfunction in Obstructive Sleep Apnea: A Systematic Review of the Literature and Meta-Analysis. Canadian Respiratory Journal No. 2017 (2017), pp.1-13.
https://search.emarefa.net/detail/BIM-1150780
American Medical Association (AMA)
Maripov, Abdirashit& Mamazhakypov, Argen& Sartmyrzaeva, Meerim& Akunov, Almaz& Muratali uulu, Kubatbek& Duishobaev, Melis…[et al.]. Right Ventricular Remodeling and Dysfunction in Obstructive Sleep Apnea: A Systematic Review of the Literature and Meta-Analysis. Canadian Respiratory Journal. 2017. Vol. 2017, no. 2017, pp.1-13.
https://search.emarefa.net/detail/BIM-1150780
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1150780