Perspectives on the Use of Ninjin’yoeito in Modern Medicine: A Review of Randomized Controlled Trials
Joint Authors
Takayama, Shin
Yasui, Hiromichi
Makino, Toshiaki
Arita, Ryutaro
Ohsawa, Minoru
Kikuchi, Akiko
Motoo, Yoshiharu
Ishii, Tadashi
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-09-02
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Background.
Ninjin’yoeito (NYT), a traditional Japanese (Kampo) medicine that originates from China, has been used to treat qi and blood deficiency based on its original concept.
Kampo medicine has been widely used to treat many conditions and disorders combined with western medicine or Kampo medicine alone in modern situation.
Aims.
We reviewed randomized controlled trials (RCTs) of NYT and discussed various standpoints regarding its use in modern situation.
Methods.
We searched PubMed, Cochrane Library, and Evidence Reports of Kampo Treatment (EKAT) for articles written in English, and Ichushi, J-Stage, and EKAT for those written in Japanese.
Articles published before January 1, 2019, were retrieved using the keywords “ninjinyoeito” and “ninjin’yoeito,” and RCTs were selected from these extracted articles.
Result.
Of 734 articles, 13 were RCTs, 46 were non-RCTs or studies of other designs, 15 were case reports, and 36 were experimental studies using NYT.
NYT was evaluated for its use as a treatment for cancer and related conditions, refractory blood diseases and conditions, and otorhinolaryngologic symptom in 13 RCTs.
Based on the use of Kampo medicine in modern situation called as Yasui’s classification, 10 of 13 RCTs were categorized as “the side effects of Western medicinal treatment are mitigated when combined with Kampo treatment” and the remaining 3 were categorized as “treatment effect of Kampo medicine is increased in combination with standard Western medicinal treatment.” Conclusion.
Several studies demonstrated the efficacy of NYT in refractory diseases and other conditions, and the accompanied side effects of treatment with western medicine.
American Psychological Association (APA)
Takayama, Shin& Arita, Ryutaro& Ohsawa, Minoru& Kikuchi, Akiko& Yasui, Hiromichi& Makino, Toshiaki…[et al.]. 2019. Perspectives on the Use of Ninjin’yoeito in Modern Medicine: A Review of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-15.
https://search.emarefa.net/detail/BIM-1151801
Modern Language Association (MLA)
Takayama, Shin…[et al.]. Perspectives on the Use of Ninjin’yoeito in Modern Medicine: A Review of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-15.
https://search.emarefa.net/detail/BIM-1151801
American Medical Association (AMA)
Takayama, Shin& Arita, Ryutaro& Ohsawa, Minoru& Kikuchi, Akiko& Yasui, Hiromichi& Makino, Toshiaki…[et al.]. Perspectives on the Use of Ninjin’yoeito in Modern Medicine: A Review of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-15.
https://search.emarefa.net/detail/BIM-1151801
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1151801