Reversed Septal Curvature Is Associated with Elevated Troponin Level in Hypertrophic Cardiomyopathy

Joint Authors

Rajtar-Salwa, Renata
Tokarek, Tomasz
Dimitrow, Paweł Petkow

Source

Disease Markers

Issue

Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2020-11-28

Country of Publication

Egypt

No. of Pages

6

Main Subjects

Diseases

Abstract EN

The aim of study was to compare patients with hypertrophic cardiomyopathy divided according to septal configuration assessed in a 4-chamber apical window.

The study group consisted of 56 consecutive patients.

Reversed septal curvature (RSC) and non-RSC were diagnosed in 17 (30.4%) and 39 (69.6%) patients, respectively.

Both RSC and non-RSC groups were compared in terms of the level of high-sensitivity troponin I (hs-TnI), NT-proBNP (absolute value), NT-proBNP/ULN (value normalized for sex and age), and echocardiographic parameters, including left ventricular outflow tract gradient (LVOTG).

A higher level of hs-TnI was observed in RSC patients as compared to the non-RSC group (102 (29.2-214.7) vs.

8.7 (5.3-18) (ng/l), p=0.001).

A trend toward increased NT-proBNP value was reported in RSC patients (1279 (367.3-1186) vs.

551.7 (273-969) (pg/ml), p=0.056).

However, no difference in the NT-proBNP/ULN level between both groups was observed.

Provocable LVOTG was higher in RSC as compared to non-RSC patients (51 (9.5-105) vs.

13.6 (7.5-31) (mmHg), p=0.04).

Furthermore, more patients with RSC had prognostically unfavourable increased septal thickness to left LV diameter at the end diastole ratio.

Patients with RSC were associated with an increased level of hs-TnI, and the only trend observed in this group was for the higher NT-proBNP levels.

RSC seems to be an alerting factor for the risk of ischemic events.

Not resting but only provocable LVOTG was higher in RSC as compared to non-RSC patients.

American Psychological Association (APA)

Rajtar-Salwa, Renata& Tokarek, Tomasz& Dimitrow, Paweł Petkow. 2020. Reversed Septal Curvature Is Associated with Elevated Troponin Level in Hypertrophic Cardiomyopathy. Disease Markers،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1154070

Modern Language Association (MLA)

Rajtar-Salwa, Renata…[et al.]. Reversed Septal Curvature Is Associated with Elevated Troponin Level in Hypertrophic Cardiomyopathy. Disease Markers No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1154070

American Medical Association (AMA)

Rajtar-Salwa, Renata& Tokarek, Tomasz& Dimitrow, Paweł Petkow. Reversed Septal Curvature Is Associated with Elevated Troponin Level in Hypertrophic Cardiomyopathy. Disease Markers. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1154070

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1154070