Evaluation of Efficacy and Safety of Dan’e-Fukang Soft Extract in the Treatment of Endometriosis: A Meta-Analysis of 39 Randomized Controlled Trials Enrolling 5442 Patients

Joint Authors

Li, Yantao
Li, Te
Song, Shilin

Source

Evidence-Based Complementary and Alternative Medicine

Issue

Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-14, 14 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2017-02-27

Country of Publication

Egypt

No. of Pages

14

Main Subjects

Medicine

Abstract EN

Objective.

To systematically evaluate the efficacy and safety of Dan’e-fukang soft extract in endometriosis treatment.

Method.

PubMed, CNKI, Wanfang Database, VIP, SinoMed, and Cochrane Library were searched.

Randomized controlled trials (RCTs) comparing the efficacy of Dan’e-fukang soft extract and conventional western medicines for endometriosis treatment were included.

The data were extracted independently by two people and analyzed using RevMan 5.2.0 software.

The relative risk (RR) and mean difference (MD) with 95% confidence intervals were considered as effective outcome indicators.

Results.

Thirty-nine papers including 5442 patients with endometriosis were included in this study.

A meta-analysis revealed that Dan’e-fukang soft extract was more efficient than gestrinone in the treatment of endometriosis (RR = 1.08, 95% CI = 1.03 to 1.15, I2 = 71%, REM, 18 trials) and its efficacy was comparable to that of danazol and mifepristone.

Dan’e-fukang soft extract was also as effective as gestrinone and mifepristone in terms of relapse rate and relieving dysmenorrhea.

The incidence of adverse reactions was lower than that of conventional western medicines.

Conclusions.

The results of this study showed that Dan’e-fukang soft extract offers certain advantages in endometriosis treatment, but rigorously designed, strictly implemented RCTs are needed to further validate its efficacy.

American Psychological Association (APA)

Li, Yantao& Li, Te& Song, Shilin. 2017. Evaluation of Efficacy and Safety of Dan’e-Fukang Soft Extract in the Treatment of Endometriosis: A Meta-Analysis of 39 Randomized Controlled Trials Enrolling 5442 Patients. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-14.
https://search.emarefa.net/detail/BIM-1155070

Modern Language Association (MLA)

Li, Yantao…[et al.]. Evaluation of Efficacy and Safety of Dan’e-Fukang Soft Extract in the Treatment of Endometriosis: A Meta-Analysis of 39 Randomized Controlled Trials Enrolling 5442 Patients. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-14.
https://search.emarefa.net/detail/BIM-1155070

American Medical Association (AMA)

Li, Yantao& Li, Te& Song, Shilin. Evaluation of Efficacy and Safety of Dan’e-Fukang Soft Extract in the Treatment of Endometriosis: A Meta-Analysis of 39 Randomized Controlled Trials Enrolling 5442 Patients. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-14.
https://search.emarefa.net/detail/BIM-1155070

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1155070