Evaluation of Efficacy and Safety of Dan’e-Fukang Soft Extract in the Treatment of Endometriosis: A Meta-Analysis of 39 Randomized Controlled Trials Enrolling 5442 Patients
Joint Authors
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-02-27
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Objective.
To systematically evaluate the efficacy and safety of Dan’e-fukang soft extract in endometriosis treatment.
Method.
PubMed, CNKI, Wanfang Database, VIP, SinoMed, and Cochrane Library were searched.
Randomized controlled trials (RCTs) comparing the efficacy of Dan’e-fukang soft extract and conventional western medicines for endometriosis treatment were included.
The data were extracted independently by two people and analyzed using RevMan 5.2.0 software.
The relative risk (RR) and mean difference (MD) with 95% confidence intervals were considered as effective outcome indicators.
Results.
Thirty-nine papers including 5442 patients with endometriosis were included in this study.
A meta-analysis revealed that Dan’e-fukang soft extract was more efficient than gestrinone in the treatment of endometriosis (RR = 1.08, 95% CI = 1.03 to 1.15, I2 = 71%, REM, 18 trials) and its efficacy was comparable to that of danazol and mifepristone.
Dan’e-fukang soft extract was also as effective as gestrinone and mifepristone in terms of relapse rate and relieving dysmenorrhea.
The incidence of adverse reactions was lower than that of conventional western medicines.
Conclusions.
The results of this study showed that Dan’e-fukang soft extract offers certain advantages in endometriosis treatment, but rigorously designed, strictly implemented RCTs are needed to further validate its efficacy.
American Psychological Association (APA)
Li, Yantao& Li, Te& Song, Shilin. 2017. Evaluation of Efficacy and Safety of Dan’e-Fukang Soft Extract in the Treatment of Endometriosis: A Meta-Analysis of 39 Randomized Controlled Trials Enrolling 5442 Patients. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-14.
https://search.emarefa.net/detail/BIM-1155070
Modern Language Association (MLA)
Li, Yantao…[et al.]. Evaluation of Efficacy and Safety of Dan’e-Fukang Soft Extract in the Treatment of Endometriosis: A Meta-Analysis of 39 Randomized Controlled Trials Enrolling 5442 Patients. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-14.
https://search.emarefa.net/detail/BIM-1155070
American Medical Association (AMA)
Li, Yantao& Li, Te& Song, Shilin. Evaluation of Efficacy and Safety of Dan’e-Fukang Soft Extract in the Treatment of Endometriosis: A Meta-Analysis of 39 Randomized Controlled Trials Enrolling 5442 Patients. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-14.
https://search.emarefa.net/detail/BIM-1155070
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1155070