Assessment of Intermingled Phlegm and Blood Stasis Syndrome in Coronary Heart Disease: Development of a Diagnostic Scale
Joint Authors
Fang, Ge
Wang, Bin
Zhou, Xuan
Liu, Xiao-qi
Li, Xian-tao
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-10-24
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
Intermingled Phlegm and Blood Stasis Syndrome (IPBSS) is a common feature in patients with coronary heart disease (CHD).
In clinical practice, the diagnostic agreement of clinical doctor of Chinese Medicine (CM) is poor.
We previously developed a IPBSS diagnostic scale for use by general practitioner.
Objectives.
To assess a IPBSS diagnostic scale that we previously developed for use by non-experts.
Methods.
This is a multicenter, prospective study involving eight study sites across China.
Eligible patients were adults (≥18 years) with CHD as demonstrated by a history of myocardial infarction, stenosis, or past coronary revascularization.
IPBSS was assessed using a scale that consisted of 14 items in two domains (e.g., phlegm and blood stasis).
The score range for each item was 0 to 3 points.
Maximum total score was 72 points.
Diagnostic accuracy was verified using consensus opinion by two independent experts as reference.
Results.
A total of 1,142 CHD patients were included.
IPBSS was established in 729 subjects using the IPBSS diagnostic scale.
In ROC curve analyses, at the optimal cut-off of 25.5, the sensitivity and specificity of the IPBSS scale were 67.6% and 72.4%, respectively.
The area under the ROC curve was 0.741 (95%CI: 0.711-0.772).
Conclusions.
The newly developed IPBSS scoring system showed moderate performance in diagnosing IPBSS in CHD patients.
Data from further large-scale diagnostic test accuracy studies are warranted.
This trial is registered with ChiCTR-OOC-15006599.
American Psychological Association (APA)
Zhou, Xuan& Li, Xian-tao& Liu, Xiao-qi& Wang, Bin& Fang, Ge. 2018. Assessment of Intermingled Phlegm and Blood Stasis Syndrome in Coronary Heart Disease: Development of a Diagnostic Scale. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1155254
Modern Language Association (MLA)
Zhou, Xuan…[et al.]. Assessment of Intermingled Phlegm and Blood Stasis Syndrome in Coronary Heart Disease: Development of a Diagnostic Scale. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1155254
American Medical Association (AMA)
Zhou, Xuan& Li, Xian-tao& Liu, Xiao-qi& Wang, Bin& Fang, Ge. Assessment of Intermingled Phlegm and Blood Stasis Syndrome in Coronary Heart Disease: Development of a Diagnostic Scale. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1155254
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1155254