Quantifying Liver-Stomach Disharmony Pattern of Functional Dyspepsia Using Multidimensional Analysis Methods
Joint Authors
Huang, Zhongyu
Lyu, Zipan
Hou, Zhengkun
Wu, Yuefeng
Huang, Junqing
Liu, Fengbin
Chen, Jiaxu
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-10-10
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Purpose.
This study aims to develop and validate a quantitative model for measuring severity of a typical traditional Chinese medicine (TCM) pattern for functional dyspepsia (FD) using multidimensional analysis methods including confirmatory factor analysis (CFA) and multidimensional item response theory (MIRT).
Methods.
A scale and theoretical models were constructed according to the definition of pathogenesis about “liver-stomach disharmony” patterns of FD.
With data collected from 502 patients in a cross-section study, the theoretical model was validated with CFA, and the related validity and reliability were evaluated in Amos 21.0.
By the use of the MIRT paradigm, psychometric properties of the scale were estimated and evaluated for pattern quantification.
Results.
A scale consisting of 12 items was constructed detecting three latent traits of the pattern.
The theoretical model was evaluated to be with adequate consistency with clinical data as RMSEA < 0.05, CFI = 0.94, and χ2/Df = 2.29.
As the correlation between symptoms and related pattern factors evaluated to be with adequate factor loading, the instrument is of preliminary interpretation.
Most precision of assessment could be achieved for patients with moderate severity of the pattern as shown in test information and standard error functions.
Conclusions.
An instrument with an interpretable conceptual framework was developed for pattern quantification in TCM clinical practice.
By constructing and evaluating both psychological and physical effects in a multidimensional model of the TCM pattern of FD, the paradigm raised in this article provided a valuable reference for interpreting complex diseases and theories such as FD and TCM patterns.
American Psychological Association (APA)
Huang, Zhongyu& Lyu, Zipan& Hou, Zhengkun& Wu, Yuefeng& Huang, Junqing& Liu, Fengbin…[et al.]. 2020. Quantifying Liver-Stomach Disharmony Pattern of Functional Dyspepsia Using Multidimensional Analysis Methods. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1155283
Modern Language Association (MLA)
Huang, Zhongyu…[et al.]. Quantifying Liver-Stomach Disharmony Pattern of Functional Dyspepsia Using Multidimensional Analysis Methods. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1155283
American Medical Association (AMA)
Huang, Zhongyu& Lyu, Zipan& Hou, Zhengkun& Wu, Yuefeng& Huang, Junqing& Liu, Fengbin…[et al.]. Quantifying Liver-Stomach Disharmony Pattern of Functional Dyspepsia Using Multidimensional Analysis Methods. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1155283
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1155283