Accuracy of Colon Capsule Endoscopy in Detecting Colorectal Polyps in Individuals with Familial Colorectal Cancer: Could We Avoid Colonoscopies?
Joint Authors
Alvarez-Urturi, Cristina
Fernández-Esparrach, Gloria
Ibáñez, Inés Ana
Rodríguez De Miguel, Cristina
Dedeu, Josep Maria
Bessa, Xavier
Córdova, Henry
Pellisé, Maria
Balaguer, Francesc
Ginés, Angels
Barranco, Luis
Araujo, Isis K.
Andreu, Montserrat
Llach, Josep
González-Suarez, Begoña
Castells, Antoni
Source
Gastroenterology Research and Practice
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-02-07
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Individuals with a family history of colorectal cancer (CRC) have an increased risk of CRC.
We evaluated the diagnostic yield of CCE in the detection of lesions and also two different colon preparations.
Methods.
A prospective multicenter study was designed to assess CCE diagnostic yield in a cohort of asymptomatic individuals with a family history of CRC.
CCE and colonoscopy were performed on the same day by 2 endoscopists who were blinded to the results of the other procedure.
Results.
Fifty-three participants were enrolled.
The sensitivity, specificity, PPV, and NPV of CCE for detecting advanced adenomas were 100%, 98%, 67%, and 100%.
Sensitivity, specificity, PPV, and NPV of CCE for the diagnosis of individuals with polyps were 87%, 97%, 93%, and 88%, respectively.
CCE identify 100% of individuals with significant or advanced lesions.
Overall cleanliness was adequate by 60.7% of them.
The PEG-ascorbic boost seems to improve colon cleanliness, with similar colonic transit time.
Conclusion.
CCE is a promising tool, but it has to be considered as an alternative technique in this population in order to reduce the number of colonoscopies performed.
More studies are needed to understand appropriate screening follow-up intervals and optimize the bowel preparation regimen.
American Psychological Association (APA)
Alvarez-Urturi, Cristina& Fernández-Esparrach, Gloria& Ibáñez, Inés Ana& Rodríguez De Miguel, Cristina& Dedeu, Josep Maria& Bessa, Xavier…[et al.]. 2017. Accuracy of Colon Capsule Endoscopy in Detecting Colorectal Polyps in Individuals with Familial Colorectal Cancer: Could We Avoid Colonoscopies?. Gastroenterology Research and Practice،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1156137
Modern Language Association (MLA)
Alvarez-Urturi, Cristina…[et al.]. Accuracy of Colon Capsule Endoscopy in Detecting Colorectal Polyps in Individuals with Familial Colorectal Cancer: Could We Avoid Colonoscopies?. Gastroenterology Research and Practice No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1156137
American Medical Association (AMA)
Alvarez-Urturi, Cristina& Fernández-Esparrach, Gloria& Ibáñez, Inés Ana& Rodríguez De Miguel, Cristina& Dedeu, Josep Maria& Bessa, Xavier…[et al.]. Accuracy of Colon Capsule Endoscopy in Detecting Colorectal Polyps in Individuals with Familial Colorectal Cancer: Could We Avoid Colonoscopies?. Gastroenterology Research and Practice. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1156137
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156137