Cost-Effectiveness Analysis of Helicobacter pylori Diagnostic Methods in Patients with Atrophic Gastritis
Joint Authors
Ohde, Sachiko
Deshpande, Gautam A.
Omata, Fumio
Shimbo, Takuro
Fukui, Tsuguya
Source
Gastroenterology Research and Practice
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-02-23
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Background.
There are several diagnostic methods for Helicobacter pylori (H.
pylori) infection.
A cost-effective analysis is needed to decide on the optimal diagnostic method.
The aim of this study was to determine a cost-effective diagnostic method in patients with atrophic gastritis (AG).
Methods.
A decision-analysis model including seven diagnostic methods was constructed for patients with AG diagnosed by esophagogastroduodenoscopy.
Expected values of cost and effectiveness were calculated for each test.
Results.
If the prevalence of H.
pylori in the patients with AG is 85% and CAM-resistant H.
pylori is 30%, histology, stool H.
pylori antigen (SHPAg), bacterial culture (BC), and urine H.
pylori antibody (UHPAb) were dominated by serum H.
pylori IgG antibody (SHPAb), rapid urease test (RUT), and urea breath test (UBT).
Among three undominated methods, the incremental cost-effective ratios (ICER) of RUT versus SHPAb and UBT versus RUT were $214 and $1914, respectively.
If the prevalence of CAM-sensitive H.
pylori was less than 55%, BC was not dominated, but its H.
pylori eradication success rate was 0.86.
Conclusions.
RUT was the most cost-effective at the current prevalence of CAM-resistant H.
pylori.
BC could not be selected due to its poor effectiveness even if CAM-resistant H.
pylori was more than 45%.
American Psychological Association (APA)
Omata, Fumio& Shimbo, Takuro& Ohde, Sachiko& Deshpande, Gautam A.& Fukui, Tsuguya. 2017. Cost-Effectiveness Analysis of Helicobacter pylori Diagnostic Methods in Patients with Atrophic Gastritis. Gastroenterology Research and Practice،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1156255
Modern Language Association (MLA)
Omata, Fumio…[et al.]. Cost-Effectiveness Analysis of Helicobacter pylori Diagnostic Methods in Patients with Atrophic Gastritis. Gastroenterology Research and Practice No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1156255
American Medical Association (AMA)
Omata, Fumio& Shimbo, Takuro& Ohde, Sachiko& Deshpande, Gautam A.& Fukui, Tsuguya. Cost-Effectiveness Analysis of Helicobacter pylori Diagnostic Methods in Patients with Atrophic Gastritis. Gastroenterology Research and Practice. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1156255
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156255