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Comparison between Intestinal Behçet’s Disease and Crohn’s Disease in Characteristics of Symptom, Endoscopy, and Radiology
Joint Authors
Zhang, Tianyu
Wang, Zhengting
Fan, Rong
Zhang, Maochen
Hong, Liwen
Zhou, Xiaolin
Cheng, Mengmeng
Zhong, Jie
Lin, Yun
Sun, Peijun
Lin, Xiaoyi
Source
Gastroenterology Research and Practice
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-05-31
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Aim.
To evaluate different parameters in differentiating intestinal BD from CD.
Methods.
The medical records of inpatients with intestinal BD and CD were retrospectively reviewed.
The univariate value of different parameters was analyzed, respectively.
A differentiation model was established by pooling all valuable parameters together.
Diagnostic efficacy was evaluated, and a receiver operating curve (ROC) was plotted.
Results.
Forty-two BD patients and ninety-seven CD patients were reviewed.
Demographic and clinical parameters that showed significant value included diarrhea, fever, perianal disease, oral ulcers, genital ulcers, skin lesions, and musculoskeletal lesions.
Endoscopic parameters reaching clinical significance included multiple-site lesions, lesions confined to the ileocecal region, longitudinal ulcers, round or oval ulcers, punch-out ulcers, ulcers with discrete margin, ulcer size>2 cm, stricture of bowel, and anorectal involvement.
Radiologic parameters aiding the differentiation included involvement segments≤3, asymmetrical pattern of involvement, intraluminal pseudopolyp formation, target sign, stricture with proximal dilation, comb sign, and fistula.
The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of the differentiation model were 90.5%, 93.8%, 92.8%, 86.4%, and 95.8%, respectively.
The cutoff value was 0.5 while the area under the ROC curve was 0.981.
Conclusion.
The differentiation model that integrated the various parameters together may yield a high diagnostic efficacy in the differential diagnosis between intestinal BD and CD.
American Psychological Association (APA)
Zhang, Tianyu& Hong, Liwen& Wang, Zhengting& Fan, Rong& Zhang, Maochen& Lin, Yun…[et al.]. 2017. Comparison between Intestinal Behçet’s Disease and Crohn’s Disease in Characteristics of Symptom, Endoscopy, and Radiology. Gastroenterology Research and Practice،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1156357
Modern Language Association (MLA)
Zhang, Tianyu…[et al.]. Comparison between Intestinal Behçet’s Disease and Crohn’s Disease in Characteristics of Symptom, Endoscopy, and Radiology. Gastroenterology Research and Practice No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1156357
American Medical Association (AMA)
Zhang, Tianyu& Hong, Liwen& Wang, Zhengting& Fan, Rong& Zhang, Maochen& Lin, Yun…[et al.]. Comparison between Intestinal Behçet’s Disease and Crohn’s Disease in Characteristics of Symptom, Endoscopy, and Radiology. Gastroenterology Research and Practice. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1156357
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156357