“The Therapy of Elimination First” for Early Acute Mastitis: A Systematic Review and Meta-Analysis
Joint Authors
Li, Xin
Zhou, Min
Xiaoying, Sun
Zhang, Ying
Li, Kexin
Wang, Xiaomin
Cai, Lijun
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-02
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
We evaluated the effectiveness of “the therapy of elimination first” in early acute mastitis, using four databases (CNKI, Wanfang, Embase, and PubMed).
The study incorporated 2508 patients from 16 randomized controlled trials (RCTs).
Included trials used Chinese oral medicine and applied the principle of “Eliminating Therapy” for the early treatment of acute mastitis, with simple antibiotic treatment as a control group.
Meta-analysis showed significant differences between the overall effectiveness of oral Chinese medicine using Eliminating Therapy (OCM-ET) and western medicine using antibiotics (WM-A) (odds ratio [OR] = 4.43, 95% confidence interval [CI] = 3.21–6.12, Z = 9.04, and P<0.00001).
Analysis of subgroups based on the use of classic or self-made preparations of the medicines showed smaller statistical heterogeneity among the different subgroups (P>0.05, I2≤50%).
The OCM-ET group showed significantly shorter pain relief times [mean difference (MD) = −3.08, 95% CI = (−5.90, −0.26), and P=0.03] and cure times [MD = −6.27, 95% CI = (−9.68, −2.85), and P=0.0003] than did the WM-A group.
Our findings suggest that OCM-ET can shorten the duration of pain and improve cure time in early acute mastitis patients, with fewer adverse reactions.
However, RCTs of higher quality with larger sample sizes are required to confirm these findings.
American Psychological Association (APA)
Zhang, Ying& Xiaoying, Sun& Li, Kexin& Wang, Xiaomin& Cai, Lijun& Li, Xin…[et al.]. 2018. “The Therapy of Elimination First” for Early Acute Mastitis: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1156394
Modern Language Association (MLA)
Zhang, Ying…[et al.]. “The Therapy of Elimination First” for Early Acute Mastitis: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-12.
https://search.emarefa.net/detail/BIM-1156394
American Medical Association (AMA)
Zhang, Ying& Xiaoying, Sun& Li, Kexin& Wang, Xiaomin& Cai, Lijun& Li, Xin…[et al.]. “The Therapy of Elimination First” for Early Acute Mastitis: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1156394
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156394