13C Methacetin Breath Test for Assessment of Microsomal Liver Function: Methodology and Clinical Application
Joint Authors
Gorowska-Kowolik, Katarzyna
Chobot, Agata
Kwiecien, Jaroslaw
Source
Gastroenterology Research and Practice
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-07-05
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Assessment of the liver function, and the need of constant monitoring of the organ’s capacity, concerns not only patients with primary liver diseases, but also those at risk of hepatopathies secondary to other chronic diseases.
Most commonly, the diagnostics is based on measurements of static biochemical parameters, which allow us to draw conclusions only indirectly about the function and the degree of damage of the organ.
On the other hand, liver biopsy is an invasive procedure and therefore it is associated with a considerable risk of complications.
Dynamic tests enable us to assess quantitatively the organ’s functional reserve by analyzing the kinetics of the metabolization of the substrate by the liver.
In practice applied are breath tests using substances such as aminopyrine, caffeine, methacetin, erythromycin (for assessment of the microsomal function); phenylalanine, galactose (for assessment of the cytosolic function); methionine, octanoate, ketoisocaproic acid (for assessment of the mitochondrial function).
The test with 13C methacetin belongs to the best described and most widely applied methods in noninvasive liver function assessment.
Due to the rising availability of this method, knowledge concerning its limitations and controversies regarding the methodology, as well as its usefulness in chosen groups of patients, seems to be vital.
American Psychological Association (APA)
Gorowska-Kowolik, Katarzyna& Chobot, Agata& Kwiecien, Jaroslaw. 2017. 13C Methacetin Breath Test for Assessment of Microsomal Liver Function: Methodology and Clinical Application. Gastroenterology Research and Practice،Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1156595
Modern Language Association (MLA)
Gorowska-Kowolik, Katarzyna…[et al.]. 13C Methacetin Breath Test for Assessment of Microsomal Liver Function: Methodology and Clinical Application. Gastroenterology Research and Practice No. 2017 (2017), pp.1-5.
https://search.emarefa.net/detail/BIM-1156595
American Medical Association (AMA)
Gorowska-Kowolik, Katarzyna& Chobot, Agata& Kwiecien, Jaroslaw. 13C Methacetin Breath Test for Assessment of Microsomal Liver Function: Methodology and Clinical Application. Gastroenterology Research and Practice. 2017. Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1156595
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156595